Herein, the various polymer properties and the underlying mechanism for the functionalization and surface modification of polymer nanoparticles have been discussed. There are numerous polymer particles designed and developed for various applications. The synthesis and characterization of different types of polymers followed by the engineering of nanoparticles and capsules depend on various factors. There are too many polymerization methods approached for the development of nanoparticles with desired surface properties. The ring-opening polymerization (ROP), emulsion polymerization (EP), atom transfer radical polymerization (ATRP), and free radical micro initiation are the significant approaches for the polymerization reactions. The polymer nanoparticle functionalization and modification of their surfaces based on requirements is an essential task. The solvent concentration, pH, temperature, and sonication have played a vital role to tune the morphology of polymer nanoparticles and capsules. Different characterizations such as FTIR, NMR (1 H and 13 C), HRMS, and MALDI-TOF are used for preliminary structural and confirmations. Further, SEM, FE-SEM, TEM, AFM, BET, XRD, Raman, EDAX, TGA-DSC, DLS, and zeta potential were used for morphological and thermal properties.
Herein, the amino‐acid based glycine (Gly) solubility in different solvents (ethanol, pyridine, and n‐hexane) exhibited striking interlocking behavior with mesoporous silica nanoparticles (MP‐SiO2NPs) has been reported and discussed in detail. The synthesis of MP‐SiO2NPs carried out employing the modified Stober's ‘Sol‐Gel’ method. The yielded MP‐SiO2NPs size ranges from ∼20–80 nm, with an average particle size of ca. 36 nm. The morphology of Gly bound with MP‐SiO2NPs was analyzed through electron microscopic imaging (SEM, TEM), followed by characterizations (BET, PXRD, DSC, TGA, EDAX) in various solvents. Interestingly, Gly dissolved in particular solvents demonstrated remarkable binding and interlocking properties with the well‐dispersed MP‐SiO2NPs to form a foamy surface. The developed [(Gly)‐(MPSiO2NPs)] based aggregate is stable at room temperature (∼25 °C). Further, developed [(Gly)‐(MP‐SiO2NPs)] aggregate used to load the anticancer drug (DOX) and it shows ∼80 % loading efficacy. Whereas, the DOX release from [(Gly)‐(MP‐SiO2NPs)] is calculated as ∼59 % after 24 hr. The designed nanoformulation [(Gly)‐(MP‐SiO2NPs)] aggregate along with DOX shows significant inhibition (i. e. 74 %) on K562 (chronic myeloid leukemia) blood cancer cells. Such low‐density foamy materials are believed to be utilized in industrial and pharmaceutical applications.
Indium tin oxide (ITO) is an ubiquitous transparent conducting oxide (TCO) used in various optoelectronic devices owing to its high optical transmittance and high electrical conductivity. The rarity of indium...
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