This note reports the synthesis and
peptide formation of a novel
triple G-C-T nucleobase amino acid (NBA) building block featuring
three recognition faces: DDA (G mimic), DAA (C mimic), and ADA (T
mimic). Readily obtainable in multigram scale in a remarkably easy
one-step reaction, this unique NBA building block offers scope for
wide ranging applications for nucleic acid recognition and nucleic
acid peptide/protein interaction studies.
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