Background: Anti-filarial IgG4 antibody has been shown to be a good marker for detection of lymphatic filaria infection. Previous studies demonstrated that anti-filarial IgG4 assay using BmR1 recombinant antigen was highly specific and sensitive for detection of brugian filariasis. For bancroftian filariasis, an equivalent assay employing recombinant antigen expressed from the ORF of SXP1 gene has been reported. In order to detect infections by all species of lymphatic filarial, BmR1 and BmSXP recombinant antigens were employed in the development of a pan LF-ELISA.
In the global effort to eliminate lymphatic filariasis (LF), rapid field-applicable tests are useful tools that will allow on-site testing to be performed in remote places and the results to be obtained rapidly. Exclusive reliance on the few existing tests may jeopardize the progress of the LF elimination program, thus the introduction of other rapid tests would be useful to address this issue. Two new rapid immunochromatographic IgG4 cassette tests have been produced, namely WB rapid and panLF rapid, for detection of bancroftian filariasis and all three species of lymphatic filaria respectively. WB rapid was developed using BmSXP recombinant antigen, while PanLF rapid was developed using BmR1 and BmSXP recombinant antigens. A total of 165 WB rapid and 276 panLF rapid tests respectively were evaluated at USM and the rest were couriered to another university in Malaysia (98 WB rapid, 129 panLF rapid) and to universities in Indonesia (56 WB rapid, 62 panLF rapid), Japan (152 of each test) and India (18 of each test) where each of the tests underwent independent evaluations in a blinded manner. The average sensitivities of WB rapid and panLF rapid were found to be 97.6% (94%-100%) and 96.5% (94%-100%) respectively; while their average specificities were both 99.6% (99%-100%). Thus this study demonstrated that both the IgG4 rapid tests were highly sensitive and specific, and would be useful additional tests to facilitate the global drive to eliminate this disease.
This study aims to estimate the economic value of a recreational park by using the travel cost method (TCM). Case studies have been done for Pahang National Park, Malaysia, and Srengseng urban forest, Jakarta, Indonesia. The data was obtained from a structured interview with visitors. The data was analysed by using Poisson and negative binomial model. Based on the survey result, it is known that the Srengseng urban forest is local public good used by local public residents whereas the Pahang National Park is visited by visitors from all over the world. The frequency determinants of visits to the urban forest are cost, age, occupation, gender, and visitor’s satisfaction; meanwhile, visit the national park is affected by travel cost, age, education, income and number of visits. The TCM method utilized in this research resulted in the Srengseng Urban Forest total economic benefit of RM0.44 million per year and the Pahang National Park total consumer surplus of RM15.3 million.
Purpose – The purpose of this paper is to examine the impact of using information and communication technology (ICT) on retail property in Malaysia. It also examines what listed property companies perceive in terms of the implications of using ICT in the retail property sector in Malaysia. Design/methodology/approach – Data were collected from sample surveys completed by 79 property companies listed on the Bursa Malaysia (formerly known as the Kuala Lumpur Stock Exchange). An ICT retail impact matrix was then developed to assess the significance of ICT on retail property in Malaysia. Findings – The findings of the study revealed that ICT would have only a minor impact on retail property in Malaysia and that there would still be a need for the traditional means of conducting a retail property business. It also found that the listed property companies were ready to implement ICT applications and that the demand for retail property would still increase in Malaysia in the future. Research limitations/implications – Only 66 percent of listed property companies in Malaysia (the respondents) participated in the study. Originality/value – This paper seeks to look at the impact ICT has on retail property in Malaysia. For this purpose, an ICT retail impact matrix was developed to assess this impact. As such, this study will be used as a benchmark for future ICT studies relating to retail property and the real estate sector in Malaysia.
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