Synchronous malignancy are defined as two primary malignancy of two different organs occurring concurrently or within 6 months duration. Reports of synchronous breast carcinoma with RCC (renal cell carcinoma) are very limited. We presented here the first case of non-metastatic synchronous RCC with breast carcinoma and Paget’s disease associated with tubercular axillary lymphadenitis in a 62 year old female for which she underwent right MRM and right partial nephrectomy. She received chemotherapy and anti-tubercular therapy post-surgery and currently on oral hormonal therapy. Follow up scans showed stable disease. There have been cases of breast cancer with TB lymphadenitis as well as of double synchronous malignancies involving breast carcinoma and RCC. Most of the multiple malignancies reported in literature are metastatic tumours or metachronous breast malignancy with RCC. A case of synchronous primary ca breast with pages disease coexisting with primary RCC along with tubercular lymphadenopathy is yet to be reported in literature. This might just be the first one.
Germ cell tumors (GCT) are commonly seen in both children and young adults. Teratomas are a form of GCT and histologically contain tissues derived from all three germ cell layers. These tumors can exhibit malignant behaviour, hence should be diagnosed and treated as early as possible. So, hereby present a case of 18-year-old female who presented with complaints of fever and cough with gradual onset from 20 days. A chest X-ray revealed growth in the left side of the chest. A high-resolution computed tomographic (HRCT) scan of the chest showed a large well-defined hypodense lesion in the left hilar region. Bronchoscopy showed extrinsic compression in the left main bronchus. The patient underwent anterolateral thoracotomy to remove a 9×9 cm mass lying in the mediastinum resting on pericardium. The histopathology specimen turned out to be a mature teratoma. This interesting case is described with its incidence, diagnosis and management protocols for the mediastinal teratoma.
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