The Cu-catalyzed hydroboration of alkynes in operationally simple and environmentally friendly conditions is reported.

Herein we report the one‐pot dual‐metal catalytic synthesis of arylallylamines, by combination of a Cu‐catalyzed hydroboration with a Pd‐catalyzed Suzuki arylation, using a broad range of aryl halides. Importantly, the reaction sequence was entirely performed in water, in the presence of small amounts of SPGS‐550M, without the need of solvent switch or addition of organic co‐solvents, rendering it operationally simple and environmentally benign. The usefulness of this methodology was highlighted in a short synthesis of the pharmaceutically important compound naftifine.magnified image

The phosphane (I) cyclizes in the presence of the strong base (II) to produce the phosphirane (III) which is isolated in the form of the tungsten complex (IV).

A regioselective green hydroboration of alkynes gives α‐ or β‐boryl derivatives at room temperature in water using a micellar solution.