Dear Sir,Dengue virus (DENV) infection is endemic in Mexico causing major public health problems (Gómez Dantés et al., 2014). It is transmitted largely through the vector mosquito Aedes aegypti (Brathwaite Dick et al., 2012). Increasing reports have showed dengue viremia in blood donors in endemic areas Mohammed et al., 2008) and transmission of DENV by blood transfusion has been recently documented in five cases (Stramer et al., 2012), therefore, DENV infection poses a risk for transfusion safety. DENV infection is nationally notifiable in Mexico (Rojo-Medina, 2014), but the presence of subclinical infections and the lack of recent seroprevalence studies in blood donors have prevented an accurate estimation of risk of infection by DENV through blood transfusion (Grange et al., 2014). We previously reported that 2% of blood donors from Nuevo Leon state, an endemic area for dengue in Mexico, showed anti-DENV antibodies in 2007 (Rodríguez Rodríguez et al., 2009). Our objective was to assess whether the seroprevalence of anti-DENV antibodies remains constant in blood donors over time and compare it with routine serologic markers.

No abstract

No abstract

The progression and distribution of the SARS-CoV-2 pandemic are continuously changing over time and can be traced by blood donors’ serological survey. Here, we investigated the seroprevalence of anti-SARS-CoV-2 antibodies in blood donors in Nuevo Leon, Mexico during 2020 as a strategy for the rapid evaluation of the spread of SARS-CoV-2 and asymptomatic case detection. We collected residual plasma samples from blood donors who attended two regional donation centers from January to December of 2020 to identify changes in anti-SARS-CoV-2 IgG prevalence. Plasma samples were analyzed on the Abbott Architect instrument using the commercial Abbott SARS-CoV-2 IgG chemiluminescent assay. We found a total of 99 reactive samples from 2068 analyzed plasma samples, resulting in a raw prevalence of 4.87%. Donors aged 18–49 years were more likely to be seropositive compared to those aged >50 years (p < 0.001). Weekly seroprevalence increased from 1.8% during the early pandemic stage to 27.59% by the end of the year. Prevalence was 1.46-fold higher in females compared to males. Case geographical mapping showed that Monterrey city recorded the majority of SARS-CoV-2 cases. These results show that there is a growing trend of seroprevalence over time associated with asymptomatic infection that is unnoticed under the current epidemiological surveillance protocols.

No abstract

No abstract

No abstract

No abstract