Quality of life is a comprehensive concept that includes ideals of health, psychological well-being, social relations and environmental conditions. The Quality of Life of Medical Students (CVEM) has become a notorious issue in the last decade, even in the scientific community. Increasing rates of anxiety, depression, stress, and drug use related to the college lifestyle have been reported. The objective of this work was to highlight the effectiveness of the interventions used to improve CVEM. The systematic review method was adopted to conduct the study. All stages of the review followed the PRISMA guideline. The search words "Medical Student" and "Quality of Life" were used in the databases: PubMed, ERIC, EMBASE and Scopus. Articles from the last ten years that had evaluated an intervention to improve CVEM scores were included. Ten studies of high quality according to MERSQI were included, which met the eligibility criteria, with half of the studies assessed from CVEM using the WHOQOL-BREF instrument. The interventions or assessments found were relaxation exercises, resilience and educational environment, received social support, physical activity, unified protocol for the treatment of emotional disorders, mindfulness and curricular change. We highlight the effectiveness of three studies that proposed as interventions, relaxation exercises, resilience in an educational environment, social support and implementation of a unified protocol for the treatment of emotional disorders. All of them with the purpose of showing ways in which medical schools can improve the CVEM. La calidad de vida es un concepto integral que incluye ideales de salud, bienestar psicológico, relaciones sociales y condiciones ambientales. La Calidad de Vida de los Estudiantes de Medicina (CVEM) se ha convertido en un tema notorio en la última década, incluso en la comunidad científica. Se han señalado crecientes índices de ansiedad, depresión, estrés y consumo de drogas relacionados con el estilo de vida universitario. El objetivo de este trabajo fue resaltar la efectividad de las intervenciones utilizadas para mejorar el CVEM. Se adoptó el método de revisión sistemática para realizar el estudio. Todas las etapas de la revisión siguieron la guía PRISMA. Se utilizaron las palabras de búsqueda "Medical Student" y "Quality of Life" en las bases de datos: PubMed, ERIC, EMBASE y Scopus. Se incluyeron artículos de los últimos diez años que habían evaluado una intervención para mejorar las puntuaciones del CVEM. Se incluyeron diez estudios alta calidad según MERSQI, que cumplió con los criterios de elegibilidad La mitad de los estudios evaluados CVEM utilizando el instrumento WHOQOL-BREF Las intervenciones o valoraciones encontradas fueron: ejercicios de relajación, resiliencia y ambiente educativo, apoyo social recibido, actividad física, protocolo unificado para el tratamiento de trastornos emocionales, mindfulness y cambio curricular, destacando la efectividad de tres estudios que trajeron como intervenciones: ejercicios de relajación, resiliencia en un ambiente educativo, apoyo social e implementación de un protocolo unificado para el tratamiento de los trastornos emocionales. mostrar formas en las que las escuelas de medicina pueden mejorar CVEM.
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