Lanthanide-based luminescent materials
have unique properties and
are well-studied for many potential applications. In particular, the
characteristic 5d → 4f emission of divalent lanthanide ions
such as EuII allows for tunability of the emissive properties
via modulation of the coordination environment. We report the synthesis
and photoluminescence investigation of pentamethylcyclopentadienyleuropium(II)
tetrahydroborate bis(tetrahydrofuran) dimer (1), the
first example of an organometallic, discrete molecular EuII band-shift luminescence thermometer. Complex 1 exhibits
an absolute sensitivity of 8.2 cm–1 K–1 at 320 K, the highest thus far observed for a lanthanide-based band-shift
thermometer. Opto-structural correlation via variable-temperature
single-crystal X-ray diffraction and fluorescence spectroscopy allows
rationalization of the remarkable thermometric luminescence of complex 1 and reveals the significant potential of molecular EuII compounds in luminescence thermometry.
A new family of ten dinuclear Ru(II) complexes based on the bis[pyrrolyl Ru(II)] triad scaffold, where two Ru(bpy)2centers are separated by a variety of organic linkers, was prepared to evaluate...
Reaction of aza-dipyrrins with alkali bases provides alkali salts of the anionic aza-dipyrrinato ligand. This anionic ligand source demonstrates complementary reactivity to the traditionally-used neutral pre-ligand.
The
synthesis and characterization of the first BODIPY appended
to the five-membered heterocylic tellurophene [Te] moiety is reported.
By incorporating tellurophene at the meso position,
the tellurophene-appended boron-dipyrromethene dye (BODIPY) acts as
a multimodal agent, becoming a potent photosensitizer with a mass
cytometry tag. To synthesize the compound, we developed a method to
enable late-stage Suzuki–Miyaura coupling by preparing and
isolating tellurophene-2-BPin in a one-step procedure from the parent
tellurophene. Coupling to a meso-substituted BODIPY
functionalized with a pendant aryl bromide provides the desired tellurophene-appended
BODIPY. This compound demonstrated a singlet oxygen quantum yield
of 0.26 ± 0.01 and produced a light dose-dependent cytotoxicity
with nanomolar IC50 values against 2D cultured HeLa cells
and high efficacy against 3D cultured HeLa tumor spheroids, proving
to be a strong photosensitizer. The presence of the tellurophene moiety
could be detected using mass cytometry, thus showcasing the ability
of a tellurophene-appended BODIPY as a novel photodynamic-therapy–mass-cytometry
theranostic agent.
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