Introduction: To evaluate the efficacy and safety of PreserFlo Ò MicroShunt in primary open angle glaucoma (POAG) eyes after a single failed trabeculectomy. Methods: Retrospective review of POAG eyes with a failed trabeculectomy that underwent PreserFlo Ò MicroShunt implantation from March 2019 to November 2019, in two Italian glaucoma centers. Pre-and postoperative data were collected and compared. Results: A total of 31 surgeries in 31 patients were reviewed. Mean preoperative IOP and mean preoperative number of medications were 24.12 ± 3.14 mmHg and 3.29 ± 0.64, respectively, and decreased to 12.56 ± 2.64 mmHg and 0.46 ± 0.77 at the 12-month postoperative follow-up visit (p \ 0.01). The most frequent adverse events were transient hypotony (6 eyes, 19.3%) and choroidal effusion (3 eyes, 9.6%). In all cases spontaneous resolution was observed, with no intervention.
Conclusion:In POAG eyes with a single failed trabeculectomy, the PreserFlo Ò MicroShunt was safe and effective in reducing the IOP after a 12-month follow-up. The PreserFlo Ò Micro-Shunt may represent a viable choice as a second surgery.
This multicenter prospective study found only 14 of 340 nonresponders to latanoprost. In the cross-over trial on nonresponders, IOP reduction reached statistical significance only after brimonidine, but their small number reduced its statistical power.
Aims-Ultrasound biomicroscopy was used to study the shape of the iris and the iridolenticular contact in pigment dispersion syndrome (PDS) eyes, to compare them with matched normal eyes, and to assess the morphological eVects of laser iridotomy in PDS eyes. Methods-50 eyes of 50 patients suVering from PDS (group 1), and 15 normal eyes of 15 subjects matched for age and refraction (group 2), were studied by ultrasound biomicroscopy (UBM, Humphrey-Zeiss). Nd:YAG laser iridotomy was proposed to the 30 PDS patients with concave iris and 18 underwent the treatment. Results-The iris was concave in 27 eyes in group 1, and three more eyes showed a concave iris during accommodation. After laser iridotomy, the treated irises were flatter than normal (p=0.0207), whereas the iridolenticular contact was not significantly diVerent. Conclusions-Laser iridotomy can restore a normal iris shape and iridolenticular contact in eyes suVering from PDS. (Br J Ophthalmol 1998;82:150-153)
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