Objetivo: Esse trabalho propôs verificar a prevalência de pré-obesidade, obesidade geral e central num grupo de mulheres admitidas para o tratamento de câncer de mama em uma unidade de assistência de alta complexidade (UNACON) no município de Juiz de Fora, Minas Gerais. Métodos: Foi realizado um estudo transversal descritivo incluindo 50 pacientes com câncer de mama, escolhidas por conveniência e de acordo com os critérios de inclusão nos ambulatórios de atendimento clínico em oncologia de uma UNACON, representada pela Associação Feminina de Prevenção e Combate ao Câncer de Juiz de Fora (ASCOMCER). O perfil antropométrico foi avaliado por medidas de peso, altura, índice de massa corpórea (IMC), circunferência abdominal (CA) e circunferência do quadril (CQ). Resultados: Observou-se um IMC médio de 29 kg/m 2 , sendo que 38% das pacientes estavam obesas, com IMC ≥30 kg/m 2. Em relação à CA, 92% das mulheres apresentavam medidas ≥80 cm, indicando alta incidência de obesidade central. A hipertensão arterial sistêmica (HAS) estava presente em 26% das pacientes. O grupo de mulheres em tratamento para o câncer de mama apresentou perfil antropométrico relacionado a um pior prognóstico tanto para sobrevida livre de doença quanto para sobrevida global. Neste estudo,verificamos também que mais da metade das pacientes não praticavam atividade física regular, fator de fundamental importância, uma vez que mudanças no estilo de vida com efeito na perda de peso têm demonstrado relação positiva com o prognóstico e a qualidade de vida dessas pacientes, mesmo durante o tratamento quimioterápico. Conclusão: Dessa forma, a prática de atividade física regular deve ser priorizada na atenção à saúde da mulher com câncer.
Introdução: O tratamento do câncer de mama pode provocar variação da massa corporal e das variáveis antropométricas, que podem estar associadas a pior prognóstico. Objetivo: Verificar a associação entre variáveis antropométricas e tratamento adjuvante para câncer de mama. Métodos: Realizou-se estudo transversal com 65 pacientes diagnosticadas com câncer de mama, em que a avaliação antropométrica no período pós-tratamento foi comparada com medidas do pré-tratamento contidas nos prontuários. Resultados. Constatou-se prevalência de pré-obesas (43,0%) e obesas (37,0%) nas participantes. Não foi observada variação significativa no IMC pré- e pós-tratamento (p=0,328). Na variação individual do peso no pré-/pós-tratamento, 64,62% ganharam peso e, destes, ocorreu variação superior a 10% do peso inicial em 26,15%, e em 16,92% houve um decréscimo acima de 10% do peso inicial. Conclusões. O tratamento não interferiu nas variáveis antropométricas do grupo, mantiveram-se pré-obesas e obesas durante a terapia, situação associada a pior prognóstico e risco para doenças cardiovasculares.
Introduction: Breast cancer is the most common malignancy in women worldwide, with the exception of nonmelanoma skin tumors. The initial stage of breast cancer is one of the main predictors of survival. Mammographic screening is the most effective method for an early detection of breast cancer and premalignant lesions, with an impact on reducing mortality, considering that correct positioning during the examination is a critical factor for its quality. Methods: A casecontrol study of a mammography positioning training program (MMG) in a private center specialized in breast diagnosis. In total, 200 incidences were evaluated in 50 examinations performed by two experienced techniques, 25 examinations each. Performance criteria were evaluated in the mediolateral oblique (MLO) and craniocaudal (CC) views. In the CC, well-demonstrated lateral quadrants (QLAT), visualization of the pectoral muscle (MP), centralized nipples (MC), welldemonstrated medial quadrants (QMED), absence of pleats or folds, centralized nipples, and symmetrical breasts were considered as adequate positioning. Buck’s low positioning was considered an error criterion. In the MLO assessment, the criteria for adequate positioning were the inframammary angles (AI) visualized, nipples profiled and at the height of the MP, symmetrical breasts, absence of pleats and folds, and symmetrical MP. Pending breasts and pectoralis minor (PP) visualization were considered positioning failures. An 11-h theoretical-practical training was applied: 7 h of practice and 4 h of theory; new tests were performed and the quality criteria were reassessed. Results: Positioning errors were significantly decreased after the training. Errors in the CC incidence decreased from 39% to 11% and in the MLO from 36% to 13%. After the training, the following improved criteria were evaluated in CC: QLAT well shown rose from 50% to 94%, MP visualization rose from 21% to 62%, MC rose from 49% to 79%, QMED well shown rose from 45% to 100%, absence of pleats or folds rose from 74% to 88%, profiled nipples rose from 91% to 95%, and symmetrical breasts rose from 86% to 98%. Buck’s low positioning dropped from 19% to 0%. In the MLO incidence, the criteria that improved were: AI visualization rose from 45% to 82%, profiled nipples rose from 93% to 95%, nipples at MP height rose from 24% to 84%, absence of pleats or folds rose from 39% to 70%, symmetrical breasts rose from 90% to 100%, symmetrical MP rose from 56% to 82%, symmetrical nipples rose from 72% to 86%, and PP visualization dropped from 13% to 7%. Conclusion: The MMG positioning training program improved examination quality. It acts on a vulnerable part, which is human error. The result indicates that a simple, low-cost intervention with low technological complexity can significantly impact the quality of MMG and screening programs in our country.
Objective: Pathological complete response rate (pCR), ypT0/is ypN0, after neoadjuvant chemotherapy (NAC) varies in each molecular subtype of breast cancer, being lower in hormone receptor-positive (HR+) tumors. The objective of this study is to analyze the pathological response rate (PR) only in the breast, only in the axilla or the pCR, correlating with the molecular subtypes. Methods: This is a retrospective observational study of stage II and III patients undergoing NAC between 2013 and 2020 at the Oncology and Mastology Service of Santa Casa de Misericórdia de Belo Horizonte – MG (SCMBH). This study was approved by the Research Ethics Committee of SCMBH with the number 3,787,212 complying with Resolution 196/96 of the National Council for Ethics in Research. Results: In all, 209 patients were selected with a mean age of 50.6 years; 22.0% were T2, 35.9% were T3, and 42.1% were T4; 17.2% were pre-NAC cN0 and 82.7% were cN+. Patients were divided into group A, RH+, with 147 patients (70.3%), and group B, HER2+ and TN, with 62 patients (29.7%). When comparing PR only in the breast, RH+ patients had a better result (4.8% versus 1.6%); as well as PR only in the axilla, 37.4% against 29.0%. When subdividing group A into RH+/HER2− and RH+/HER2+, the former presented better results in the breast (4.3% X 0%) and in the axilla (60.9% X 55.6%). Conclusion: Achieving pCR is not the only goal of NAC. Other benefits include the possibility of breast and axilla-conserving surgery. The study demonstrated good PR results in both the breast and the axilla in group A and in the RH+/HER2− subgroup. These responses allow for a less morbid surgical treatment, both aesthetically and because of the risk of lymphedema. The data presented provide a compelling rationale for the use of NAC in a molecular subtype considered to be relatively resistant to chemotherapy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.