Robot-assisted gait training (RAGT) devices are used in rehabilitation to improve patients' walking function. While there are some reports on the adverse events (AEs) and associated risks in overground exoskeletons, the risks of stationary gait trainers cannot be accurately assessed. We therefore aimed to collect information on AEs occurring during the use of stationary gait robots and identify associated risks, as well as gaps and needs, for safe use of these devices. We searched both bibliographic and full-text literature databases for peer-reviewed articles describing the outcomes of stationary RAGT and specifically mentioning AEs. We then compiled information on the occurrence and types of AEs and on the quality of AE reporting. Based on this, we analyzed the risks of RAGT in stationary gait robots. We included 50 studies involving 985 subjects and found reports of AEs in 18 of those studies. Many of the AE reports were incomplete or did not include sufficient detail on different aspects, such as severity or patient characteristics, which hinders the precise counts of AE-related information. Over 169 device-related AEs experienced by between 79 and 124 patients were reported. Soft tissue-related AEs occurred most frequently and were mostly reported in end-effector-type devices. Musculoskeletal AEs had the second highest prevalence and occurred mainly in exoskeleton-type devices. We further identified physiological AEs including blood pressure changes that occurred in both exoskeleton-type and end-effector-type devices. Training in stationary gait robots can cause injuries or discomfort to the skin, underlying tissue, and musculoskeletal system, as well as unwanted blood pressure changes. The underlying risks for the most prevalent injury types include excessive pressure and shear at the interface between robot and human (cuffs/harness), as well as increased moments and forces applied to the musculoskeletal system likely caused by misalignments (between joint axes of robot and human). There is a need for more structured and complete recording and dissemination of AEs related to robotic gait training to increase knowledge on risks. With this information, appropriate mitigation strategies can and should be developed and implemented in RAGT devices to increase their safety.
Proportional control using surface electromyography (EMG) enables more intuitive control of a transfemoral prosthesis. However, EMG is a noisy signal which can vary over time, giving rise to the question what approach for knee torque estimation is most suitable for multi-day control. In this study we compared three different modelling frameworks to estimate knee torque in non-weight-bearing situations. The first model contained a convolutional neural network (CNN) which mapped EMG to knee torque directly. The second used a neuromusculoskeletal model (NMS) which used EMG, muscle tendon unit lengths and moment arms to compute knee torque. The third model (Hybrid) used a CNN to map EMG to specific muscle activation, which was used together with NMS components to compute knee torque. Multi-day measurements were conducted on ten able-bodied participants who performed non-weight bearing activities. CNN had the best performance in general and on each day (Normalized Root Mean Squared Error (NRMSE) 9.2 ± 4.4%). The Hybrid model (NRMSE 12.4 ± 3.4%) was able to outperform NMS (NRMSE 14.3 ± 4.2%). The NMS model showed no significant difference between measurement days. The CNN model and Hybrid models had significant performance differences between the first day and all other days. CNNs are suited for multi-day torque estimation in terms of error rate, outperforming the other two model types. NMS was the only model type which was robust over all days. This study investigated the behavior of three model types over multiple days, giving insight in the most suited modelling approach for multi-day torque estimation to be used in prosthetic control.
Choosing the right features is important to optimize lower limb pattern recognition, such as in prosthetic control. EMG signals are noisy in nature, which makes it more challenging to extract useful information. Many features are used in the literature, which raises the question which features are most suited for use in lower limb myoelectric control. Therefore, it is important to find combinations of best performing features. One way to achieve this is by using a genetic algorithm, a meta-heuristic capable of searching vast feature spaces. The goal of this research is to demonstrate the capabilities of a genetic algorithm and come up with a feature set that has a better performance than the state-of-the-art feature set. In this study, we collected a dataset containing ten able-bodied subjects who performed various gait-related activities while measuring EMG and kinematics. The genetic algorithm selected features based on the performance on the training partition of this dataset. The selected feature sets were evaluated on the remaining test set and on the online benchmark dataset ENABL3S, against a state-of-the-art feature set. The results show that a feature set based on the selected features of a genetic algorithm outperforms the state-of-the-art set. The overall error decreased up to 0.54% and the transitional error by 2.44%, which represent a relative decrease in overall errors up to 11.6% and transitional errors up to 14.1%, although these results were not significant. This study showed that a genetic algorithm is capable of searching a large feature space and that systematic feature selection shows promising results for lower limb myoelectric control.
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