monochromator slit width. (Increasing the lamp current would also reduce UBE.) However, in none of the cases investigated would this produce a significant reduction in the total absorbance noise. (Even if up were reduced to zero, OA would not be reduced by more than 30% in any case.) In addition, increasing the lamp current or slit width would lead to a reduction of the absorbance signal in many cases and consequently have a detrimental effect on the detection limit.Lamp flicker noise can be reduced by using a double beam system to monitor changes in lamp intensity. However, if the lamp duty cycle is unchanged, the double beam system necessitates halving the time of observation of the lamp. This
The antimicrobial activity previously attributed to flavanone Mannich bases was found to be due to their breakdown products, 3-methyleneflavanones. Among the latter compounds, highest potency was observed when the flavanone phenyl ring contained bromine or chlorine substituents. 3-Methylene-2-phenylflavanone (8) was synthesized and shown to be equal to hexachlorophene in tests against representative Gram-positive microorganisms.
A series of 34 beta-arylamidoacrylic acids was prepared and examined for antiinflammatory activity. These compounds are vinylogous carbamic acids, and several displayed activity equal to phenylbutazone in the rat pleural effusion model. Highest activity was associated with structures bearing halogen and cyano substituents. Amides were inactive.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.