In August and September 1993, we investigated an outbreak of legionnaires' disease in Fall River, Massachusetts, that involved 11 persons; the attack rate was highest in Flint, a community of Fall River. All cases were infected with Legionella pneumophila serogroup 1 (Lp-1). A case-control study revealed that cases were more likely than matched controls to have visited sites in neighborhood A of Flint. Environmental sampling in Flint found that four of nine aerosol-producing devices sampled contained legionellae; only two, conjoined cooling towers on building A, contained Lp-1. Three independent methods of subtyping--monoclonal antibody subtyping, arbitrary primer polymerase chain reaction, and pulsed-field gel electrophoresis--revealed that Lp-1 isolates from three cases with culture-positive legionnaires' disease matched those from the cooling towers on building A. Water samples from the homes of cases with culture-positive legionnaires' disease contained no legionellae. The results of this epidemiologic and laboratory investigation indicate that the cooling towers on building A were the source of the outbreak of legionnaires' disease and confirm the importance of cooling towers in the transmission of legionnaires' disease.
Predictions of scintillation for ground to space collimated Gaussian beams generated from a numerical wave optics simulation are compared with recent weak scintillation theory developed from the Rytov perturbation approach (L.Significant discrepancies are revealed for intermediate-sized beams, defined as beams whose initial diameters place the near ground turbulence in the transmitter near field and the remote space target in the transmitter far field. By adding wander tracking to the wave optics simulation, and by developing a separate analytic model of the beam wander scintillation mechanism, we show that the scintillation for intermediate-sized beams is dominated by turbulence-induced beam wander at the target, and that the results from the wave optics simulation are accurate. We conclude that the analytic theory's treatment of beam wander is incomplete, leading to the output of incorrect predictions for the second moment of irradiance. The error is most severe at the target point on the transmitter's optical axis.
A nine-aperture, wide-field Fizeau imaging telescope has been built at the Lockheed-Martin Advanced Technology Center. The telescope consists of nine, 125 mm diameter collector telescopes coherently phased and combined to form a diffraction-limited image with a resolution that is consistent with the 610 mm diameter of the telescope. The phased field of view of the array is 1 murad. The measured rms wavefront error is 0.08 waves rms at 635 nm. The telescope is actively controlled to correct for tilt and phasing errors. The control sensing technique is the method known as phase diversity, which extracts wavefront information from a pair of focused and defocused images. The optical design of the telescope and typical performance results are described.
Recent papers comparing weak-scintillation data from waveoptics simulations with predictions derived from the Rytov perturbation method for ground-to-space Gaussian beams have revealed a region of inaccuracy in the Rytov-based predictions. The discrepancy region is defined by beam diameter and focus settings that place the target in the beam far field and the turbulence in the transmitter near field. Under such conditions turbulence-induced beam wander dominates the scintillation at the target. We develop a solution to the turbulent propagation physics that is applicable in the discrepancy region, and demonstrate agreement in scintillation behavior with our own wave-optics simulation data and with predictions from a rigorous extended Huygens-Fresnel analysis. A combination of our solution and Rytov-based scintillation theory can be used to yield accurate scintillation predictions throughout the weak-scintillation regime for ground-to-space beams. Separately, we show that Rytov-based scintillation theory best describes the physics of a wander-tracking transmitter ͑where beam wander has been removed from the propagation physics͒ at the mean transmitter aim point on the target plane, as opposed to the physics of a stationary transmitter. © 2005 Society of Photo-Optical Instrumentation Engineers.
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