Go with the flow: A simple flow reactor has been developed to accommodate highly absorbing [RuL3]2+ photosensitizers for light‐starved photoredox reactions (see picture). The use of vessels having a thin diameter increases the efficiency of the reaction. This methodology has been applied to the divergent synthesis of C‐glycoconjugates.

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A mild, stereoselective method for the Ni-catalyzed synthesis of alpha-C-alkylglycosides is reported. This approach entails the reductive coupling of glycosyl bromides with activated alkenes at room temperature, with low alkene loading as an important feature. Diastereoselective coupling with 2-substituted acrylate derivatives was made possible through the use of 2,4-dimethyl-3-pentanol as a proton source.

The photoreduction of glucosyl halides to generate glucosyl radicals has been investigated to probe the nature of the photoredox cycle. Amine (the reductant) and catalyst concentration affect the reaction rate at low concentrations but exhibit saturation at higher concentrations. Water and hydrophobic catalysts were found to significantly increase the conversion efficiency.