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This treatment program is feasible and effective in patients with advanced oropharynx cancer and produces an excellent functional outcome in most long-term survivors. Modifications to optimize patient selection, minimize toxicity, and improve local control are indicated. The relative toxicity, efficacy, and functional outcome provided by this and other chemotherapy and RT programs versus either standard surgery and/or RT options can only be addressed in a randomized comparison of these therapies.

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In response to a recent article by Guthrie and Wiener (1966) data and logical considerations are presented which support the following conclusions.( 1 ) For a number of recent studies of subliminal phenomena, the most parsimonious explanation for positive results is one implicating the subliminal registration of content and, contrary to the claim oE Guthrie and Wiener, not one relating to structural cues in awareness.( 2 ) Also contrary to their claim, Guthrie and Wiener's data provide little support for the view that even in the early investigation of Eagle ( 1 9 5 9 ) , Ss were responding to parrial cues.( 3 ) Guthrie and Wiener's failure to obtain a content effect in their own experiment was most likely the result of the level at which their stimuli were exposed and/or their not taking into account subject variables that are relevant to the question of whether a subliminal effect can be demonstrated.