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This study develops and tests a model examining the interrelationships and relative importance of management characteristics, business strategy and industry structure as influences on the performance of new, technology based companies. For a sample of 36 companies the founding managers had a sizeable influence on the quality of the industry/strategy positions, though exogenous forces were even more important; and regardless of source, industry/strategy positions exerted important influence on performance. Management characteristics influenced success through implementation, in addition to their influence on industry/strategy. The study demonstrates the effect of the founding managers on the eventual performance of a new venture. It suggests that formulation of the initial concept and execution of that concept call upon different characteristics, and therefore may be separable. That is, one group might initially devise the plan and another carry it out.entrepreneurship, strategy, structural models, technological ventures

A study was conducted to compare the regeneration across 1.4-cm peroneal nerve gaps in rats, repaired with sutured autografts or with artificial nerve grafts. The artificial models were composed of a biodegradable passive conduit made of glycolide trimethylene carbonate, filled with either phosphate-buffered saline or a collagen extracellular matrix. Functional recovery was evaluated by walking track analysis throughout the experiment. After 9 months, the nerves were analyzed by electrophysiology and by qualitative and quantitative histology. Walking track analysis demonstrated the three repair methods to provide statistically equivalent recovery, except at day 195 post-engraftment, when the collagen-filled conduit was superior to the saline-filled conduit. Electrophysiologically, the autograft was superior to the collagen-filled conduit, while the collagen- and saline-filled conduits were equivalent. Quantitative histology demonstrated that normal intact nerve had larger mean myelinated axonal diameters but an equal number of axons to the three repair methods, and that the repair methods were statistically equivalent. While the repair methods had similar histologic and functional outcomes, combined standardized scoring demonstrated that the autograft was superior to the statistically-equivalent entubulation repairs. A collagen gel may serve as an ideal matrix in which to suspend neurotrop(h)ic factors or cells.

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