Diabetic ketoacidosis is usually associated with type 1 diabetes; however, it is increasingly being recognised in type 2 diabetes. The three main mechanisms suggested are: insulinopaenia, elevation in counter‐regulatory hormones as a stress response, and increase in free fatty acids. This review aims to highlight the mechanism of diabetic ketoacidosis in type 2 diabetes, the difference compared to its occurrence in type 1 diabetes, the main triggers and its management. The most common mechanism is relative insulin deficiency (insulinopaenia) and usual triggers are non‐concordance or infection. Treatment is exactly the same as in type 1 diabetes with intravenous fluid resuscitation and insulin, though the duration of treatment may not be as long. These patients are able to stop insulin following resolution of ketoacidosis and can be managed on oral hypoglycaemic agents. It is important for clinicians to be aware of this condition due to the increasing burden of type 2 diabetes and to avoid unnecessary treatment with insulin in the long term.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.