Summary 1 In a double-blind, placebo-controlled, randomised, cross-over study of six healthy male subjects, the effect of nicardipine (5 mg h-1 for 3 h) on basal and stimulated pituitary hormone release was examined. 2 Statistically significant differences between nicardipine and placebo were seen occasionally for follicle-stimulating hormone, luteinising hormone and prolactin, but not for thyroidstimulating hormone. These differences were always within the between-batch coefficient of variation of the assay. 3 The overall differences in both basal and stimulated results for all four pituitary hormones were not statistically significantly different. 4 It is concluded, therefore, that nicardipine has no significant effect on either basal or stimulated pituitary hormone release in healthy male subjects.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.