Background: The SARS-CoV-2 infection has triggered a global health crisis. Early detection of COVID-19 infection using hematology and radiology examination is the fastest method to detect the infection. This study aims to evaluate the characteristics of sign and symptom, hematology, and radiology examination of COVID-19 patients at Universitas Gadjah Mada (UGM) Academic Hospital, Yogyakarta, Indonesia.Methods: This is a retrospective study with quantitative descriptive methods and uses a total sampling technique. This study was conducted at UGM Academic Hospital, with a total sample of 147 patients diagnosed with COVID-19. Data were collected from medical records and were analyzed with Microsoft Excel for Windows.Results: This study showed that the most signs and symptoms of COVID-19 patients were cough (46.26%) and cold (37.41%), followed by hypertension (31.97%). Hematology examination showed that the leukocyte count of patients was mainly higher than the normal level (82.99%). The data showed that 22.45% of patients had increased C-Reactive Protein (CRP) and 2.72% of patients had increased procalcitonin. The result of thorax x-ray (16.33%) and CT-scan (28.57%) examination of the COVID-19 patients indicates pneumonia.Conclusions: This study illustrated that the symptoms of COVID-19 patients at UGM Academic Hospital, Yogyakarta were various. Respiratory problems such as cough and cold were the most common symptoms, followed by muscle fatigue and digestive disorders. Hematology and radiology test results of COVID-19 patients depend on the severity of the disease.
Latar Belakang: Hipokalemia merupakan gangguan elektrolit yang sering terjadi. Hipokalemia berat dapat mengancam jiwa. Koreksi hipokalemi yang tepat dan cepat dapat mencegah komplikasi yang membahayakan jiwa. Salah satu intervensi yang dapat dilakukan adalah dengan pemberian KCl melalui akses vena perifer, tetapi KCl memiliki sifat iritatif yang dapat menyebabkan nyeri. Cara yang dapat dilakukan untuk mengurangi nyeri adalah dengan pemberian lidokain intravena. Lidokain merupakan obat anestesi yang dapat diberikan secara intravena dan memberikan efek analgesia. Tujuan: Mengetahui keefektifan lidokain untuk mengurangi nyeri pada pemberian KCl melalui akses vena perifer.Metode: Penelitian ini merupakan uji klinis randomisasi samar berganda melibatkan 37 pasien hipokalemia yang memerlukan koreksi. Pasien terbagi menjadi 21 pasien kelompok perlakuan (mendapatkan lidokain saat koreksi) dan 16 pasien kelompok kontrol (tanpa lidokain) yang kemudian penilaian nyeri menggunakan numering pain rating scale (NPRS) pada pertengahan proses koreksi (2,5 jam) dan akhir koreksi (5 jam). Hasil: Tidak terdapat perbedaan karakteristik dasar di kedua kelompok pada awal penelitian. Pemberian lidokain terbukti dapat mengurangi terjadinya nyeri dari proses koreksi kalium pada pertengahan proses koreksi dan akhir proses koreksi (p<0,05). Pada progresivitas nyeri, pemberian lidokain mampu mencegah terjadinya nyeri pada 2,5 jam pertama (RR=0,47, 95%IK 0,26-0,85, p=0,01) namun progresivitas nyeri 2,5 jam berikutnya tidak bermakna secara statistik (RR=0,95, 95%IK 0,30-2,99, p>0,05).Kesimpulan: Lidokain dapat mengurangi nyeri selama proses koreksi kalium sehingga dapat dipertimbangkan untuk diaplikasikan dalam praktik klinis.
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