Intraday trading is popular among traders due to its ability to leverage price fluctuations in a short timeframe. For traders, real-time price predictions for the next few minutes can be beneficial for making strategies. Real-time prediction is challenging due to the stock market’s non-stationary, complex, noisy, chaotic, dynamic, volatile, and non-parametric nature. Machine learning models are considered effective for stock forecasting, yet, their hyperparameters need tuning with the latest market data to incorporate the market’s complexities. Usually, models are trained and tested in batches, which smooths the correction process and speeds up the learning. When making intraday stock predictions, the models should forecast for each instance in contrast to the whole batch and learn simultaneously to ensure high accuracy. In this paper, we propose a strategy based on two different learning approaches: incremental learning and Offline–Online learning, to forecast the stock price using the real-time stream of the live market. In incremental learning, the model is updated continuously upon receiving the stock’s next instance from the live-stream, while in Offline-Online learning, the model is retrained after each trading session to make sure it incorporates the latest data complexities. These methods were applied to univariate time-series (established from historical stock price) and multivariate time-series (considering historical stock price as well as technical indicators). Extensive experiments were performed on the eight most liquid stocks listed on the American NASDAQ and Indian NSE stock exchanges, respectively. The Offline–Online models outperformed incremental models in terms of low forecasting error.
Background: Thalassemia is a chronic debilitating disease that affects nearly 200 million people worldwide. A caregiver who has good knowledge regarding the disease can not only provide a better quality of care to his/her ward but also may spread knowledge in the society in which he/she lives which helps immensely in raising community awareness related to the disease.Methods: 50 caregivers (either mother or father) of chronically transfused thalassemic children were questioned regarding their knowledge, attitude and practice towards this disease, using a self-constructed questionnaire.Results: It was found that despite adequate knowledge regarding every aspect of this disease, there is a lack of attitude of practice towards prevention of this disease in their subsequent child or in their near and dear ones.Conclusions: There is a need to promote an attitude of practice in prevention of the birth of thalassemic children as mere knowledge regarding the disease is not enough in the present scenario where the disease burden is increasing as is the financial and emotional burden on the families. Role of Government sponsorship, a social worker and a child psychologist in the Thalassemia day care unit cannot be minimized.
Background: The world adopts DOTS strategy for TB control thought the national TB control programs in different countries and is making good progress. Despite the positive therapeutic effects, studies have shown that utilization of multidrug regimens can cause undesirable adverse drug reactions (ADRs) of varying degrees of severity, such as hepatotoxicity, gastrointestinal disorders, allergic reactions, arthralgia, neurological disorders and non-adherence to treatment as well. Methods: The study was conducted on new smear positive patients registered under DOTS in two Treatment Units (TUs) present in Amritsar city. The prevalence of various adverse effects like gastro-intestinal, hepato-biliary, visual disturbances, musculoskeletal, skin and appendages, peripheral nervous system, etc was recorded and their effect on the outcome was observed. Data management and analysis was done by using Microsoft excel and SPSS version 17.00. Results: Out of 250 patients, 149 (59.6%) were males and 101(40.4%) were females. Out of the total 250 cases, adverse effects were present in 44.4% cases. Most common adverse effects observed were gastrointestinal in 63.9% followed by fever and chills in 28.8% of cases. Conclusions: On statistical analysis, it was observed that the absence of adverse effects was significantly associated with the favourable outcome (p<0.001).
Angioma serpiginosum is a rare benign vascular condition which is characterized by the presence of multiple, minute, erythematous angiomatous macules or patches present in linear blaschkoid, gyrate, or serpiginous patterns. It usually affects lower extremities and buttocks. Involvement of upper trunk and extremities is rare. Histologically, there is dilatation of blood vessels in papillary dermis. Dermoscopic findings reveal presence of oval-to-round red lagoons. It shows female preponderance. Hence, we report a rare case of angioma serpiginosum in a male child with bilateral distribution.
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