Synthesis and Biocidal Activity of Some New 2-Amino-4,6-diarylsubstituted-pyrimidines.-Base-catalyzed condensation of substituted acetophenones (I) with aromatic aldehydes affords chalcones (III) which react with guanidinium nitrate to furnish the title pyrimidines (V) (17 examples). All the compounds prepared are screened for their antibacterial and herbicidal activities. -(KOTHARI, S.; SINGHAL, M.; VIJAYVERGIA, D.; VYAS, R.; VERMA, B. L.; J. Indian Chem.
A series of substituted 1,3,4-oxadiazole derivatives (3a–f) and (6a–f) have been synthesized from diphenylacetic acid hydrazide under microwave irradiation in various reaction conditions. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, and 1H NMR. These targeted compounds have been tested for their antibacterial and antifungal activities compared to ampicillin and griseofulvin as standard drug. Compounds 3a, 3e, 3f, 6c, 6d, 6e, and 6d exhibited the maximum antibacterial activities while 3b, 3c, 3d, 3e, 6a, 6d, and 6e exhibited the maximum antifungal activities.
file. -Some of the products exhibit moderate to strong activity against strains of bacteria and/or fungi. -(VYAS, R.; SWARNKAR, N.; SANCHETI, A.; VERDIA, J.; PUNJABI*, P. B.; J. Indian Chem. Soc. 85 (2008) 12, 1217-1226; Microwave Chem. Lab., Dep. Chem., Coll. Sci., M. L. Sukhadia Univ., Udaipur 313 001, India; Eng.) -C. Cyrus 40-154
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.