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Higher cryopreserved vessel WIT was associated with increased risk-adjusted loss of primary patency in this cohort. At 1 year, the overall primary patency was 51% and amputation-free survival was 74%. Vascular surgeons should be aware that WIT may affect outcomes for lower extremity bypass.

Table). HbA 1c level was not significantly associated with AFS. Survival analysis (Kaplan-Meier plots) revealed that a diagnosis of diabetes was significantly associated with worse AFS in the entire cohort (log-rank test, P ¼ .011; Fig) as well as in the critical limb ischemia subgroup (logrank test, P ¼ .049; Rutherford >3; not pictured). Logistic regression demonstrated an association with age (P ¼ .040; adjusted odds ratio [AOR], 1.027), postoperative creatinine level (P ¼ .003; AOR, 1.247), nonwhite race (P ¼ .048; AOR, 0.567), and insulin-only diabetic control (P ¼ .002; AOR, 2.535) with worse AFS across all limbs surveyed. Conclusions: Patients with diabetes on an insulin-only regimen have significantly worse AFS than nondiabetic patients or those on an insulin-sensitizing regimen. This may represent a surrogate for disease severity, but the type of medications may present a modifiable risk factor to improve limb salvage.

ypT0 cases, the overall survival was 91.1%, not significantly different (P ¼ .25) compared with the remaining group (87.2%). Among ypT0 cases, the relapse-free survival was 94.5%, which was significantly different (P ¼ .03) compared with the remaining group (78.2%). There were no treatment-associated fatalities. Thirty-two patients (10.96%) experienced Grade III/IV toxicities (proctitis, epithelitis, and neutropenia). Conclusion: Tumor localization was identified as a predictive factor for pCR in LARC treated with preoperative chemoradiation. Upper rectal tumors are more likely to develop complete responses. Delay in surgery was identified as a favorable predictive factor for TRG1-3. The relapse-free survival in pCR group was higher compared with non-pCR.

Repeated carotid endarterectomy versus carotid artery stenting for patients with carotid restenosis after carotid endarterectomy: systematic review and meta-analysis.