Cutaneous and subcutaneous metastases from internal malignancies are rare and indicate a dismal outcome for the patient. This study is designed to analyze cases of cutaneous and subcutaneous metastases from a known or unknown primary and evaluate usefulness of fine needle aspiration cytology as a diagnostic modality. The present study is a retrospective analysis of 83 patients who were diagnosed with metastatic skin deposits on fine needle aspiration cytology. Seventy-four patients were previously diagnosed cases of malignancy and nine patients had metastatic deposits simultaneously with the primary tumor. The commonest malignancies showing cutaneous metastases were from breast, colon and rectum, lung, ovary, and thyroid. The differential diagnoses are from primary cutaneous tumors. FNAC provides a rapid diagnosis and should be used as a preferred first line diagnostic modality in such patients. In our study, FNAC yielded a sensitivity and specificity of 100% as a microscopic method for confirmation.
Introduction- : Conducting Bone marrow examination in a Hodgkin's Lymphoma (HL) patient at the time of diagnosis is done routinely to determine the stage of the disease. The aim of this study was to analyze the incidence and prognosis of bone marrow involvement in patients with Hodgkins lymphoma, retrospectively.
Materials and Patients: Ten patients of Hodgkins lymphoma were incorporated in the current study. Bone marrow aspiration and biopsy was done in all ten cases as part of staging procedure.
Results: Three patients showed involvement of bone marrow by Hodgkin’s lymphoma and both the patients had clinically poor outcome.
Discussion and Conclusion: Bone marrow examination is important in stage II and III of Hodgkin”s lymphoma because positive result will upstage the disease. Also, bone marrow involvement indicates an aggressive disease and poor prognosis for the patient.
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