Marchiafava-Bignami disease (MBD) is a rare neurological disorder of chronic alcoholism characterized by demyelination and necrosis of corpus callosum. In this case report we present the MR imaging findings of MBD and review of the other imaging features of the disease.
OBJECTIVEDetection of acute strokes along with assessment of size of infarct core and penumbra with computed tomography perfusion (CTP) imaging. METHODThirty patients with signs and symptoms of acute cerebrovascular accident underwent a plain CT scan (NCCT) followed by CTP and a follow-up NCCT or Diffusion-weighted MRI (DWI) within 7 days from symptom onset. RESULTOf the total 29 patients with acute ischaemic stroke confirmed by followup DWI, NCCT correctly detected 18 cases of acute ischaemic infarction (64.28%), whereas CTP could correctly detect 24 cases of acute ischaemic infarction (85.7%). Out of the 24 patients with abnormal perfusion CT studies found during the study period, there were total of 69 aspects areas of perfusion abnormalities with 48 areas of infarct core and 21 areas of perfusion mismatch. CONCLUSIONCTP is much more sensitive than NCCT in detection of acute stroke and CTP can also detect penumbra area in shorter investigation time as compared to DWI, proving its usefulness in planning for thrombolysis.
BACKGROUND Coronary artery disease is one of the leading causes of death in India. Evaluation of the coronary artery can be done by CT, MRI or conventional angiography and conventional angiography is the gold standard. Convention angiography is invasive, expensive, has fewer complication and not easily available. CT coronary angiography is accurate, non-invasive, easily available and has fewer complications. In this study usefulness of performing CT coronary angiography prior to convention angiography is assessed. The purpose of study was to determine the cost effectiveness of performing CT coronary angiography prior to conventional angiography in patients with suspected coronary artery disease. METHODS Patients with chest pain suspected to have coronary artery disease underwent CT coronary angiography. Patients were referred to conventional angiography only if significant stenosis was identified on CT coronary angiography. Cost effectiveness of performing CT coronary angiography before conventional angiography was compared with patients directly going for conventional angiography. RESULTS 19 patients (63.3%) had normal coronary arteries and 5 patients (16.6%) had non-significant stenosis (<50%). 6 patients (20%) had significant stenosis (>50%) and were referred for conventional angiography. Assessment of cost incurred showed performing CT coronary angiography before conventional angiography could reduce the cost up to 50%. CONCLUSIONS In patients with suspected to have coronary artery disease, performing CT coronary angiography prior to invasive angiography can reduce the cost by up to 50%.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.