Epilepsy is a chronic neurologic disorder that may complicate pregnancy, about 25%-33,3% epileptic seizures increasedin pregnancies. The main concern in pregnancies complicated by epilepsy includes the increased risk of congenitalabnormalities associated with antiepileptic drugs. Hormones can have major effect on seizure disorders. Women withepilepsy will have changes in seizure patterns when hormones levels shift, such as during pregnancy or right afterpregnancy. A woman with seizure disorder must be managed effectively to minimize the risk of a seizure that couldharm the fetus. Seizures can harm the developing fetus by reducing the blood supply to the placenta. Anti-convulsantmedications should not be discontinued during pregnancy. medications may be switched to those that are known to bethe safest to the developing fetus. This will reduce the risk for neural tube defects like spina bifida. Multiple drugtherapy should be avoided – if possible– and drugs should be given in divided doses to avoid high peak levels. We canprovide women with epilepsy with the available information, advise on the best treatment prior to pregnancy, andwarnings that most AEDs carry a risk above that of untreated epilepsy. Treatment should be planned in womenanticipating pregnancy
Attention-deficit / hyperactivity disorder (ADHD) has been associated with childhood epilepsy. Epilepsy are themost common neurologic disturbance in child age. Children with epilepsy tend to get one or more ADHD symptoms,its related to lack of norepinephrine neurotransmitter in brain, that cause attenuate the effect of GABA and disruptionto fronto-striatal brain networks, these same brain networks are disrupted by seizures or the structural brainabnormalities that can cause seizures. Children with epilepsy especially absance, tend to get inattentive type ofADHD more than other types. Abnormalities of electro-encephalography found in inattentive type of ADHD withhigh focus activities in all lobe area. No data published that methylphenidate can lower seizure threshold or act asproconvulsant. Children with epilepsy tend to get one or more symptoms of ADHD in the following days.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.