The United States Enviuomntal Protetion Agency's Offic of utsficde lPram s (Off) requires that daa from toxicity testing be submitted to the OPP to support the registration of pesticide chemicals. Once the toxcity data are submitted, they are entered into various toicity d t he studies are listed in an archival database tocatao and alow retrieval of the study for review. Reviews of toxicity studies are then placed into a separate database that can be retrieved to support a regulatory position. Toxicity infonnation for health effects other than cancer and genemutations from chronic exposure is reviewed through a reference dose (RID) approach, and these decisions and supporting data are entered into an RfD database. Carcinogenicty data are reviwed by a peerreview process, and these decisionsare entered into a newly developed database to show the reglatory decidon with support data. The mutagenicity data are reviewed and acceptable data are entered into the Genetic Activity Profile system to catalog and display the submitted infornation. These databases contain the information used for hazard evaluations as part of the OPP review of pesticide chemicals.
The United States Enviuomntal Protetion Agency's Offic of utsficde lPram s (Off) requires that daa from toxicity testing be submitted to the OPP to support the registration of pesticide chemicals. Once the toxcity data are submitted, they are entered into various toicity d t he studies are listed in an archival database tocatao and alow retrieval of the study for review. Reviews of toxicity studies are then placed into a separate database that can be retrieved to support a regulatory position. Toxicity infonnation for health effects other than cancer and genemutations from chronic exposure is reviewed through a reference dose (RID) approach, and these decisions and supporting data are entered into an RfD database. Carcinogenicty data are reviwed by a peerreview process, and these decisionsare entered into a newly developed database to show the reglatory decidon with support data. The mutagenicity data are reviewed and acceptable data are entered into the Genetic Activity Profile system to catalog and display the submitted infornation. These databases contain the information used for hazard evaluations as part of the OPP review of pesticide chemicals.
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