The clinical aspects of rheumatic heart disease in relation to pregnancy are reviewed in a combined series of patients chiefly from the Newcastle General Hospital studied over a period of 28 years, and from the Western General Hospital in Edinburgh studied over 25 years. In both centres, since about I960, there has been a progressive decrease in the number of patients found in antenatal clinics to have rheumatic heart disease, and also in the severity of this condition. There has also been a significant fall in the incidence of major complications, such as pulmonary oedema, right heart failure, and atrialfibrillation which formerly were often encountered. In addition to the changes in the natural course of the disease, improved medical management of the more severe cases, together with the introduction of cardiac surgery, has been responsiblefor a much more favourable course in the pregnant patient. The disadvantages and potential dangers of the New York Heart Association classification are emphasized and illustrated. The risks of valvotomy during pregnancy are no greater than in cases of comparable severity in the nonpregnant state. Subsequent close medical supervision is important because complications may still occur later in pregnancy. Likewise should pregnancy occur after successful valvotomy, close observation throughout is essential. Current concepts ofmedical, surgical, and obstetric management are outlined. Routine medical examinations at about IO, I5, and 20 years of age with appropriate management would render pregnancy virtually safefor every patient with rheumatic heart disease. As judged by the number of new patients found at present to have rheumatic heart disease when examined in antenatal clinics in Newcastle, Edinburgh, and in three other regions of Scotland (Szekely, i968; Turner, I968b; R. W. D. Turner and N. M. B. Dean, i969, unpublished data), and by the decreasing frequency of serious complications during pregnancy such as pulmonary oedema, right heart failure, and atrial fibrillation, the prevalence and the severity of rheumatic heart disease have declined in recent years. A similar trend has recently been reported from London (Barnes, I970). A recent inquiry carried out by one of us regarding the number of first mitral valvotomies performed anually since its introduction in i8 centres of cardiac surgery in Britain also confirms the clinical impression of a continuing decline in the incidence and severity of rheumatic heart disease in this country (R. W. D.