A syndrome in newborn infants consisting of green stools, normal number of bowel movements, without pyrexia, dehydration, vomiting or death, is described.
No etiologic agent was uncovered but metabolic changes as evidenced by low prothrombin and absence of urobilinogen in the feces and urine were seen.
The appearance of normal bacteriologic flora of the feces as evidenced by culture, smear and the presence of urobilinogen, and normal prothrombin activity following treatment suggest that a penicillin-sensitive agent which exerted antibiotic effects on the normal intestinal flora was present.
A fatal case of infantile toxoplasmosis with autopsy findings is described, bringing to 21 the number of acceptable autopsied cases. The characteristic central nervous system necrosis and calcification were present in this case. In addition, focal chorioretinitis, involvement of the spinal cord and of the periorbital and paravertebral striated muscles and the heart were present. Of great interest is the finding of testicular involvement which has been described in only one other previous case.
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