Many beneficial metabolic effects resulting from dermolipectomy and liposuction procedures are described in the literature. In particular, fasting plasma insulin and thus insulin sensitivity seem to be positively influenced. Further research, including prospective clinical studies, is necessary for better exploration of the effects that body-contouring plastic surgery procedures have on metabolic parameters.
Introduction Eyelid malignant melanoma represents less than 1 % of all skin melanomas and approximately 1 % of all malignant neoplasms of the eyelid skin. Because of its relative rarity, there is a paucity of descriptive papers reporting only small series of reconstructed patients. The repair of eyelid defects represents a reconstructive challenge. Ideally, the reconstruction of the defect must guarantee function with tissue of the same color, texture, and thickness of that of the removed skin and at the same time avoid complications such as ectropion and lagophthalmos. Materials and Methods We describe a consecutive series of 11 patients affected by cutaneous melanoma of the lower lid who underwent full-thickness excision of the neoplasm and subsequent wide excision. All the patients were treated in one-stage reconstruction modality with a modified monopedicle myocutaneous flap, harvested from omolateral upper eyelid, tunneled under the lateral canthus skin and armed with a conchal auricular cartilage framework. Four patients underwent the sentinel lymph node biopsy during reconstructive procedure. No major complications were reported. In our experience, the proposed myocuta-neous flap allows to obtain excellent results, both aesthetically and functionally. Conclusions This technique has the advantage of avoiding multi-staged procedures, with respect for the oncological excision indication for head and neck melanoma, decreasing the incidence of associated major complications.
RésuméLe cancer de la prostate est la deuxième tumeur la plus fréquemment diagnostiquée chez les hommes. Elle est responsable d’un impact significatif sur la mortalité ou la qualité de vie des patients, mais, contrairement à d’autres tumeurs, est parfois une maladie à lente progression.Une détection précoce avec dosage de lʼantigène prostatique spécifique (PSA) et un toucher rectal doit être proposé à tout sujet masculin bien informé sur ses conséquences.Le double but du dépistage est de diagnostiquer les cancers potentiellement mortels ou causant une morbidité importante, tout évitant la mise en place d’investigations et traitements agressifs pour des maladies de bas grade, surtout chez les patients âgés.Le PSA est un marqueur sensible mais non spécifique et son dosage doit être accompagné d’un contexte clinique précis, pour éviter la réalisation de biopsies superflues.Lʼimagerie par résonance magnétique multiparamétrique est un examen essentiel avant l’éventuelle réalisation d’une biopsie ainsi que pour la stadification et le suivi du cancer de la prostate (CaP).Des nouveaux biomarqueurs plus spécifiques sont attendus de longue date pour améliorer la détection précoce du CaP.
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