Cam-type deformities were recognizable and present from the age of 13 years and were more prevalent in soccer players than in their nonathletic peers. Cam-type deformity develops during adolescence and is likely to be influenced by high-impact sports practice.

Analysis 4.1. Comparison 4 Delivery of exercise: supervised versus home exercise programme, Outcome 1 Usual pain

We recommend to develop clear clinical criteria for PF OA and to reach consensus on the definition of PF OA by both radiographs and MRI. Additionally, more understanding is necessary to be able to distinguish PF symptoms from those arising from the tibiofemoral joint. More insight is needed on effective treatment strategies for PF OA; specifically, tailoring nonpharmacological treatments to individuals with PF OA, and determining whether isolated PF OA requires different treatment strategies than combined PF and tibiofemoral OA.

Structural abnormalities of the patellofemoral joint have been hypothesized as a factor in the pathogenesis of PFP, but the study findings suggest that structural abnormalities of the patellofemoral joint on MRI are not associated with PFP.

PurposeTo identify the optimal combination of pharmacokinetic model and arterial input function (AIF) for quantitative analysis of blood perfusion in the patellar bone using dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI).Materials and MethodsThis method design study used a random subset of five control subjects from an Institutional Review Board (IRB)‐approved case–control study into patellofemoral pain, scanned on a 3T MR system with a contrast‐enhanced time‐resolved imaging of contrast kinetics (TRICKS) sequence. We systematically investigated the reproducibility of pharmacokinetic parameters for all combinations of Orton and Parker AIF models with Tofts, Extended Tofts (ETofts), and Brix pharmacokinetic models. Furthermore, we evaluated if the AIF should use literature parameters, be subject‐specific, or group‐specific. Model selection was based on the goodness‐of‐fit and the coefficient of variation of the pharmacokinetic parameters inside the patella. This extends previous studies that were not focused on the patella and did not evaluate as many combinations of arterial and pharmacokinetic models.ResultsThe vascular component in the ETofts model could not reliably be recovered (coefficient of variation [CV] of vp >50%) and the Brix model parameters showed high variability of up to 20% for kel across good AIF models. Compared to group‐specific AIF, the subject‐specific AIF's mostly had higher residual. The best reproducibility and goodness‐of‐fit were obtained by combining Tofts' pharmacokinetic model with the group‐specific Parker AIF.ConclusionWe identified several good combinations of pharmacokinetic models and AIF for quantitative analysis of perfusion in the patellar bone. The recommended combination is Tofts pharmacokinetic model combined with a group‐specific Parker AIF model. Level of Evidence: 2 Technical Efficacy: Stage 1J. Magn. Reson. Imaging 2018;47:848–858.