Background Dermoscopy can be helpful in assessing nonpigmented lesions and inflammatory processes like lichen planopilaris (LPP). Material & Methods In this observational prospective study, 81 patients with a cicatricial alopecic patch on their scalp were included and underwent dermatologic examination. A biopsy was taken from the active part of the lesion based on dermoscopy evaluation. Results Analysis of 44 patients with definite diagnosis of LPP revealed that the mean age at the time of presentation was 44.05 ± 12.62 years. More than 77% of patients had at least one form of the follicular opening disorder. About 75% of patients had shaft disorders. The most common pattern of pigmentation was milky‐red (97.73%). The irregular and ectatic vascular network were seen in 59.09% of patients. Patients with coiled and twisted hairs, small yellow dots, large yellow dots, and peripilar sign were more likely to have shorter disease duration (P < 0.05). Those with overall shaft disorders were younger (P = 0.02). Small yellow dots (P = 0.025) and peripilar sign (P = 0.039) were more common in female patients. Conclusion Dermoscopy can be a helpful diagnostic tool in differentiating LPP among patients with primary cicatricial alopecia (PCA). Larger cohort studies are recommended to find the role of demographic factors in predicting the dermoscopic patterns among LPP patients.
Objective: Lichen planopilaris (LPP) is a rare skin disorder, but it is also the most common cause of scarring alopecia in adults. The main cause of this disease is unknown, but it is considered to be related to the immune status of the body. Several comorbidities are reportedly associated with LPP, such as hypertension, depression, thyroiditis, diabetes, and vitiligo. In the present study, we aimed to investigate the frequency of comorbidities in patients with LPP who were referred to Razi Hospital in Rasht, Iran, from 2016 to 2019.Methods: This cross-sectional study involved 60 patients with cicatricial alopecia patches (scarring and irreversible) and clinical signs and symptoms consistent with active LPP. The association between demographic data and comorbidities in patients with LPP was evaluated with the chi-square test and t test. Results:The results showed that the most common comorbidities were vitamin D deficiency (24.3%), hypothyroidism (17.6%), anemia (16.2%), asthma and allergy (14.8%), hypertension (13.5%), diabetes (9.5%), and vitiligo (4.5%). There was no statistically significant association of sex, age, or body mass index with LPP according to the presence or absence of underlying disease (P = 0.440, P = 0.108, and P = 0.340, respectively); however, there was a statistically significant difference in the presence of comorbidities according to age (P = 0.018). Conclusion:The results illustrated that women with vitamin D deficiency are more prone to LPP than are patients with other pre-existing underlying diseases.
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