The occurrence of a neoplasm of a cell type different from that found in the normal organ is always of considerable interest. Eighty‐five cases of either pure squamous cell carcinoma or adenosquamous cell carcinoma of the stomach have been reported to date with an incidence calculated in different series between 0.04 and 0.7%. Its sex ratio is 4:1 in favor of men. The theories of the pathogenesis of such tumors with unexpected cell types have been reviewed. To the authors, prior squamous cell metaplasia of the gastric mucosa seems essential for the pathogenesis of the pure type of this unusual neoplasm, but, in the mixed tumor, either squamous differentiation in an adenocarcinoma or in a cell capable of differentiating along both cell types appears more likely. An additional case of the mixed type is added to the literature.
A case of endometriosis of the urinary bladder in a man is described. The patient had been treated with estrogen for several years following radical prostatectomy and orchiectomy for prostatic carcinoma. The only other reported case of endometriosis in a male presented in a strikingly similar manner. Pathogenic speculations are briefly presented.
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