Background: Spleen is a large encapsulated mass of vascular and lymphoid tissue. Clinically, study of spleen is important in immunological and haematological disorders. The purpose of the study is to analyse the morphological variations of spleen and to compare them with previous studies.Materials and methods: The present study was carried out with 35 spleens at the Department of Anatomy, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur and the various morphological variations were observed.Results: Out of the 35 spleens studied, 6 spleens were tetrahedral, 12 spleens were triangular, 15 spleens were wedge shaped and 2 spleens were oval shaped. The mean length was 10.91cm, the mean breadth was 6.7cm and the mean width was 4.9cm.Conclusions: 35 normal spleens were studied and their shapes, lengths, breadths, widths were analysed.
Background: To study the histogenesis of the prostate gland in human foetuses. ‘Prostates’ is a Greek word which literally means “one who stands before”, protector, guardian. It is important from a clinical point of view as it undergoes benign enlargement from the fifth decade, hence attracting the attention of males around this age and simultaneously the clinicians. Materials and Methods: 100 foetuses of different gestational ages ranging from 14 weeks (85 mm) to 40 weeks (440 mm), products of terminated pregnancies under Medical Termination of Pregnancy, MTP Act of India, 1971 and stillbirths were collected from the Department of Obstetrics and Gynaecology, RIMS, (Regional Institute of Medical Sciences), Imphal, Manipur and utilised for the present study with permission from the Institutional Ethical Committee. Results and Discussion: The first sign of differentiation is recognised as increased cellularity and denser mesenchymal cells. Cytoarchitecture at specific age period at different age groups are described. Conclusion: Cytoarchitecturally, differentiation of all the three components of the prostate gland was noted as the age changes. It is inferred that of the three components of the adult tissues, the glandular component is differentiated from the epithelial lining of the urethra. This further induces the early mesenchymal tissues to differentiate into muscles and fibrous components. And at term, it has all the three components of the adult tissues although it is not as mature as in adult. KEY WORDS: Prostate gland, human foetuses, histogenesis and cytoarchitecture.
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