It is important to understand the mechanism of polymerization, mechanical properties, and environmental and temperature effects of polymethylmethacrylate.» The liquid component of bone cement comprises methylmethacrylate monomer, N,N-dimethyl-p-toluidine, hydroquinone, and possibly dye.» The powder component of bone cement contains benzoyl peroxide, beads of polymethylmethacrylate, possibly dye, zirconium dioxide or barium sulfate radiopacifier, and antibiotics. » Up to 2 g of powdered antibiotics added to a 40-g package probably does not compromise the integrity of the cement.» Preheating the implant or heating during polymerization is controversial but does not appear to strongly negatively affect the mechanical properties of the bone cement.

Fondaparinux is an effective drug for VTE prophylaxis in total joint arthroplasty with wound drainage and LOS comparable to historical controls of enoxaparin, warfarin, and rivaroxaban.