Cellular identities in the past have been based on the structural and functional aspects. Proper delineation of cellular structure occasionally could be
ambiguous because of their varied existence either structurally similar or functionally dissimilar or vice versa. “Ghost cells”- is an area which is
entailed by controversies allocated to their functionality and appearance. In odontogenic lesions they are considered as the enlarged epithelial cells
with central space consequential to lost nucleus. Many authors have documented on the histogenesis and formation of ghost cells yet nothing
relevant till date. This article is an attempt to concise the literature in precise manner to elaborate the ghost cell origin in histopathologic arena.
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