Aspirin (2-acetoxybenzoic acid), or acetylsalicylic acid, is an anti-inflammatory, analgesic and antipyretic medication (Banihani, 2019; Yin, Yamamoto, & Gaynor, 1998). It is one of the nonsteroidal anti-inflammatory drugs (NSAIDs) (Webb et al., 2019). Currently, aspirin is extensively used to increase the thinning effect of the blood or reduce the blood clots as it inhibits the function of platelets (Jia et al., 2019; Shen et al., 2019; Xu et al., 2019). Therefore, as urgent medical practice, to reduce the risk of death, aspirin is highly recommended just after the event of a heart attack (Dalen, 2006; McNeil et al., 2018). However, recurrent use of aspirin has been found to have serious adverse effects such as stomach bleeding and stomach ulcer (Chen et al., 2017; Taha, McCloskey, McSkimming, & McConnachie, 2018). Biochemically, aspirin suppresses the formation of prostaglandins and thromboxanes (Gimenez-Bastida, Boeglin, Boutaud, Malkowski, & Schneider, 2019; Rauzi et al., 2016) since it irreversibly inactivates cyclooxygenase (prostaglandin-endoperoxide synthase), which is an enzyme that catalyses the formation of prostanoids such as prostaglandins (e.g. prostacyclin) and thromboxane from