Background: The most severe form of nervous dysfunction among young individuals is Multiple sclerosis (MS). Symptoms usually appear at (15–40) years of age.MS is identified as an affective disorder in patients for a long time, characterized by current nervous system (NS) injury structure and rising accumulative damage.Recent years have seen a rise in the number of MS. This affects more than two million individuals every year in the world. Methods: Ethical approval for this study was granted by the Ethics Committee for the Medical Research/University of Mosul. This was a retrospective and a hospital-based study performed. In the latter, MS patients' medical records fulfilling the McDonald diagnostic criteria were analyzed, and both demographics and clinical characteristics were reviewed. We did exclude patients with neuromyelitis optica and isolated transverse myelitis. A retrospective study design was applied in Ibn-Sina Teaching Hospital, City of Mosul, Iraq. Results:This section summarizes the main findings of this research. Identified 500 patients who fulfilled our criteria for having MS. The crude estimated Prevalence of MS in the Mosul population was thus 50/100,000. The research population's demographic and clinical characteristics were identified and found a positive first or second-degree family history of MS at least 11.4% of Mosul patients. Conclusion:Based on the assumptions and previous studies that patients with multiple sclerosis in Mosul suffer from milder disease severity than those in western countries, it was surprising that half of the patients suffer from gait disability.
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