Triclosan is a broad-spectrum antimicrobial agent that has been incorporated into many household and medical products. Bacteria with high levels of triclosan resistance were isolated from compost, water, and soil samples. Two of these bacteria, Pseudomonas putida TriRY and Alcaligenes xylosoxidans subsp. denitrificans TR1, were able to use triclosan as a sole carbon source and clear particulate triclosan from agar. A decrease in triclosan concentration was measured by HPLC within 6 h of inoculation with strain TriRY and 24 h with strain TR1. Bioassays demonstrated that triclosan was inactivated in liquid cultures and/or embedded in plastic by the growth of strain TriRY and strain TR1, permitting the growth of triclosan-sensitive bacteria.
Myoglobin is shown to bind to mixed thin films of docosyl mesylate and methyl docosanoate. Myoglobin
can be attached to films containing docosyl mesylate; however, films containing only methyl docosanoate
exhibit only minimal myoglobin attachment. This indicates that myoglobin is specifically attached to the
docosyl mesylate sites on the film surface. Surface coverage of myoglobin is dependent on the percentage
of docosyl mesylate in the film. A maximum myoglobin coverage of approximately 1.2 × 1012 myoglobin/cm2
is estimated for films composed of between 22% and 30% docosyl mesylate.
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