Diagnostic laparoscopy has been performed ever since inter ests in infertility and fertility have developed. Methylene blue is administered to check tubal patency during the procedure. Extravasation of methylene blue is a recognized complication of diagnostic laparoscopy and chromopertubation. Anaphy laxis and anaphylactic reactions in the perioperative period are a significant concern for surgeons and anesthesiologists. The incidence is as high as 1 in 3,500 with a mortality rate of 3 to 6%. 16 There are no relevant literature or research article that provides sufficient data or guidelines for determining the nature of these reactions, mode of treatment algorithm, or the certain specifications we should consider before performing the procedure. This is a review literature for performing a safe practice evaluation and management.
Diagnostic laparoscopy has been performed ever since inter ests in infertility and fertility have developed. Methylene blue is administered to check tubal patency during the procedure. Extravasation of methylene blue is a recognized complication of diagnostic laparoscopy and chromopertubation. Anaphy laxis and anaphylactic reactions in the perioperative period are a significant concern for surgeons and anesthesiologists. The incidence is as high as 1 in 3,500 with a mortality rate of 3 to 6%.16 There are no relevant literature or research article that provides sufficient data or guidelines for determining the nature of these reactions, mode of treatment algorithm, or the certain specifications we should consider before performing the procedure. This is a review literature for performing a safe practice evaluation and management.
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