Diabetes is one of the most rapidly-growing chronic diseases in the world. Acetone, a volatile organic compound in exhaled breath, shows a positive correlation with blood glucose and has proven to be a biomarker for type-1 diabetes. Measuring the level of acetone in exhaled breath can provide a non-invasive, low risk of infection, low cost, and convenient way to monitor the health condition of diabetics. There has been continuous demand for the improvement of this non-invasive, sensitive sensor system to provide a fast and real-time electronic readout of blood glucose levels. A novel nanostructured K2W7O22 has been recently used to test acetone with concentration from 0 parts-per-million (ppm) to 50 ppm at room temperature. The results revealed that a K2W7O22 sensor shows a sensitive response to acetone, but the detection limit is not ideal due to the limitations of the detection system of the device. In this paper, we report a K2W7O22 sensor with an improved sensitivity and detection limit by using an optimized circuit to minimize the electronic noise and increase the signal to noise ratio for the purpose of weak signal detection while the concentration of acetone is very low.
Diabetes, one of the most rapidly-growing chronic diseases in the world, is overall relative expensive on both diagnosis and monitoring. Breath acetone has proven to be a biomarker of diabetes which is a metabolite with a strong correlation with blood glucose. Measuring the concentration of acetone in exhaled breath can provide a non-invasive, low risk of infection, low cost, and convenient way to screen diabetics at the early stage and daily monitor the health condition of diabetics. Several materials have been investigated for their ability to detect of breath acetone. The preliminary results show that nanostructured K 2 W 7 O 22 (KWO), a new functional semiconducting material, synthesized by hydrothermal method, can effectively detect breath acetone at room temperature. This paper emphasizes that the sensing performance of KWO on breath acetone. In addition, a comparison between KWO with other materials for application in sensing acetone is discussed.
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