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BackgroundIsolated small gut mesentery injury after blunt abdominal trauma from the steering wheel in road traffic accidents is rare. These are always challenging to diagnose and pose a diagnostic dilemma.ObjectivesTo study the pattern of small gut mesenteric injury by steering wheel blunt abdominal trauma in road traffic accidents in patients who had laparotomy.Patients and MethodsA 10-year retrospective study was done to study isolated small gut mesentery injury.ResultsAll patients who had isolated mesenteric small gut injury were males. Jejunal mesentery was involved in 13 whereas 4 had ileal mesentery injury. Tear were longitudinal or transverse.ConclusionsIsolated small mesentery injury after blunt abdominal trauma from the steering wheel in road traffic accidents is rare. Tears are either longitudinal or transverse. Suture repair is to be done. Delay in reaching hospital or reaching the diagnosis could lead to morbidity and mortality. Isolated mesenteric injury should be considered in any patient with blunt abdominal trauma from steering wheel injury with no evidence of any solid organ injury in unstable patients.

S‐Methyl‐β‐N‐(3‐(2‐nitrophenyl)allylidene)dithiocarbazate (HL), Schiff base of S‐methyl dithiocarbazate, was synthesized by 1:1 condensation between S‐methyl dithiocarbazate and trans‐o‐Nitrocinnamaldehyde. It's in‐vitro cytotoxicity is assayed against two habitually infection causing bacteria strains including gram‐positive Staphylococcus aureus and gram‐negative Escherichia coli for antibacterial activity. The results showed appreciable biological activity and the activity increased with increase in concentration. This nitrogen‐sulfur based Schiff base (HL) was characterized by Mass, FT‐IR, 1H‐NMR, 13C‐NMR, Raman, and UV‐Vis spectroscopic techniques. Theoretical quantum chemical calculation has been performed using DFT in combination with B3LYP exchange correlation functional and 6‐311++ G (d, p) basis sets level. The computed parameters were: Chemical potential of compound (μ) −0.174 eV, HOMO‐LUMO energy gap −0.11093 eV, chemical hardness (ɳ) −0.055 eV, softness (S) 2.164 eV, ionization energy (IE) −0.23026 eV, electron affinity (EA) −0.11933 eV, the electronegativity (EN) 0.174 eV, dipole moment (D) 1.3383 Debye and relative stabilization energy −1536.982 eV. In the theoretical FT‐IR spectrum analysis 81 fundamental vibrational modes has be observed because of non‐linear structure of HL, with potential energy distribution percentage (PED%) by using VEDA‐4 (Vibrational energy distribution analysis) software. Theoretically calculated parameters like 1H‐NMR, 13C‐NMR, FT‐IR, UV‐VIS, Raman, electrostatic potential and HOMO‐LUMO energy gap were in conformity with experimental results.

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MicroRNAs (miRNAs) are small non-coding RNAs that control the expression of genes by targeting specific mRNAs. Data related to miRNAs are limited for fish species, with only 16 out of the 30 000 fish species enlisted in miRBase. In the present review, we have summarized the recent findings on the implication of miR-NAs in the teleost reproduction with an emphasis on commercially important candidates. The information related to various miRNAs and their roles during different developmental stages of gonads in nine important species has been compiled. We have focused on the trend of sexual dimorphism in the gonadal miRNA repertoire of teleost species. Species-specific variability is observed in the expression pattern of gonadal miRNAs in both male and female fish. It is noteworthy that our summarization of teleost miRNAs in reproduction has highlighted the gaps in functional information on the identified miRNAs (both conserved and novel). It is only after functional validation of the miRNA targets, one can use these findings to enhance reproductive health and production of the commercial teleost species to boost overall aquaculture sector.

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