Early detection, rapid cessation of the transfusion, early consultation with the hematologic and ICU departments, and fluid resuscitation are all necessary for the initial management of blood transfusion reactions. It is crucial that doctors stay current with the literature, are knowledgeable of the pathophysiology, early therapy, and hazards of each type of transfusion reaction because blood transfusions can result in major adverse consequences. Immune-mediated transfusion responses frequently result from a mismatch or incompatibility between the recipient and the transfused substance. Monitoring the patient's respiration rate, blood pressure, temperature, and pulse rate is necessary. Abnormal clinical characteristics, such as fever, rashes, or angioedema, should also be constantly evaluated.
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