Intestinal amoebiasis and sequelae such as amoebic liver abscess are rarely reported in the era of modern medicine. Atypical presentation of amoebic liver abscess with high false-positive results on serology in endemic regions poses major diagnostic issues in the developing nations of the world. We report a case of amoebic liver abscess and describe the imaging appearances in a 59-year-old female. A detailed medical history was elicited to determine the etiology of amoebic liver abscess. Furthermore, the diagnosis was confirmed based on serological tests. Percutaneous aspiration of the amoebic liver abscess was performed, and treatment was initiated with intravenous metronidazole followed by diloxanide furoate. The patient has been on follow-up since three months with a negative stool examination and with no complaints of recurrence.
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