Epilepsy, a neurological disorder, is characterized by the recurrence of seizures. Electroencephalogram (EEG) signals, which are used to detect the presence of seizures, are non-linear and dynamic in nature. Visual inspection of the EEG signals for detection of normal, interictal, and ictal activities is a strenuous and time-consuming task due to the huge volumes of EEG segments that have to be studied. Therefore, non-linear methods are being widely used to study EEG signals for the automatic monitoring of epileptic activities. The aim of our work is to develop a Computer Aided Diagnostic (CAD) technique with minimal pre-processing steps that can classify all the three classes of EEG segments, namely normal, interictal, and ictal, using a small number of highly discriminating non-linear features in simple classifiers. To evaluate the technique, segments of normal, interictal, and ictal EEG segments (100 segments in each class) were used. Non-linear features based on the Higher Order Spectra (HOS), two entropies, namely the Approximation Entropy (ApEn) and the Sample Entropy (SampEn), and Fractal Dimension and Hurst Exponent were extracted from the segments. Significant features were selected using the ANOVA test. After evaluating the performance of six classifiers (Decision Tree, Fuzzy Sugeno Classifier, Gaussian Mixture Model, K-Nearest Neighbor, Support Vector Machine, and Radial Basis Probabilistic Neural Network) using a combination of the selected features, we found that using a set of all the selected six features in the Fuzzy classifier resulted in 99.7% classification accuracy. We have demonstrated that our technique is capable of achieving high accuracy using a small number of features that accurately capture the subtle differences in the three different types of EEG (normal, interictal, and ictal) segments. The technique can be easily written as a software application and used by medical professionals without any extensive training and cost. Such software can evolve into an automatic seizure monitoring application in the near future and can aid the doctors in providing better and timely care for the patients suffering from epilepsy.

Epilepsy is a global disease with considerable incidence due to recurrent unprovoked seizures. These seizures can be noninvasively diagnosed using electroencephalogram (EEG), a measure of neuronal electrical activity in brain recorded along scalp. EEG is highly nonlinear, nonstationary and non-Gaussian in nature. Nonlinear adaptive models such as empirical mode decomposition (EMD) provide intuitive understanding of information present in these signals. In this study a novel methodology is proposed to automatically classify EEG of normal, inter-ictal and ictal subjects using EMD decomposition. EEG decomposition using EMD yields few intrinsic mode functions (IMF), which are amplitude and frequency modulated (AM and FM) waves. Hilbert transform of these IMF provides AM and FM frequencies. Features such as spectral peaks, spectral entropy and spectral energy in each IMF are extracted and fed to decision tree classifier for automated diagnosis. In this work, we have compared the performance of classification using two types of decision trees (i) classification and regression tree (CART) and (ii) C4.5. We have obtained the highest average accuracy of 95.33%, average sensitivity of 98%, and average specificity of 97% using C4.5 decision tree classifier. The developed methodology is ready for clinical validation on large databases and can be deployed for mass screening.

The proposed system is automated and hence is more objective, can be easily deployed in any computer, is fast and accurate and can act as an adjunct tool in helping physicians make a confident call about the nature of the ovarian tumor under evaluation.

Epilepsy is a chronic brain disorder which manifests as recurrent seizures. Electroencephalogram (EEG) signals are generally analyzed to study the characteristics of epileptic seizures. In this work, we propose a method for the automated classification of EEG signals into normal, interictal and ictal classes using Continuous Wavelet Transform (CWT), Higher Order Spectra (HOS) and textures. First the CWT plot was obtained for the EEG signals and then the HOS and texture features were extracted from these plots. Then the statistically significant features were fed to four classifiers namely Decision Tree (DT), K-Nearest Neighbor (KNN), Probabilistic Neural Network (PNN) and Support Vector Machine (SVM) to select the best classifier. We observed that the SVM classifier with Radial Basis Function (RBF) kernel function yielded the best results with an average accuracy of 96%, average sensitivity of 96.9% and average specificity of 97% for 23.6 s duration of EEG data. Our proposed technique can be used as an automatic seizure monitoring software. It can also assist the doctors to cross check the efficacy of their prescribed drugs.

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