There is a wide heterogeneity in assessment criteria for mHealth apps. It is necessary to define the exact meanings and degree of distinctness of each criterion. This will help to improve the existing tools and may lead to achieve a better comprehensive mHealth app assessment tool.

This study is aimed at determining the best nonacid nucleic blood tumor marker panels in terms of sensitivity, specificity, and accuracy in order to detect breast cancer in early stages (I, II, and III) among eligible women for breast cancer screening. PubMed, Web of Science, Embase, Scopus, and Cochrane were systematically reviewed to assess nonacid nucleic blood tumor marker panels’ diagnostic value in women, both healthy and patient (before any anticancer treatment), for detecting breast cancer. A network meta-analysis was carried out using a Bayesian network meta-analysis to estimate combined odd ratio (OR) and 95% CI credible interval for presenting the results. Rankograms plot was drawn to rank the diagnostic value of different panels. Of the 2358 titles initially identified, 9 studies and 8 panels were included in the network meta-analysis. Panels A (MMP-9/TIMP-1) and K (TF1+TF2+TF3) had the highest sensitivity in early stages, as panel A with OR = 11.61 and 95% CI (1.49-102.5) demonstrated a better function than mammography. Panels H (CA 15.3 + IL-18) and A (MMP-9/TIMP-1) had the highest specificity in early stages, but no significant difference with mammography. Panels A (MMP-9/TIMP-1) and H (CA 15.3 + IL-18) had the highest accuracy in early stages, as they significantly exhibited a higher function than mammography with OR = 6.87 and 95% CI (2.07-31.35) as well as OR = 3.44 and 95% CI (1.15-11.07), respectively. Panel A including MMP-9/TIMP-1 in early stages demonstrated a higher diagnostic value for breast cancer than the rest of the panels.

Background: There is a belief that in patients with acromegaly, first-generation somatostatin analogs (SSAs) might improve cardiovascular (CV) structure and function. However, most published clinical trials involved only a few patients and their results are rather variable. We aimed to conduct a systematic review on available studies on the impact of these drugs on CV parameters. Materials and Methods: A literature search was conducted in MEDLINE (OVID), EMBase, Cochrane, and ISI Web of Science for citations published until April 30 2018 to identify studies on our objective that considered changes in CV parameters. For this search, we established a Boolean search strategy using keywords related to “acromegaly,” “Somatostatin analog,” and “cardiovascular diseases and parameters.” All study types except for case reports or conference abstracts were included. Twenty-four studies ( n = 558) fulfilled the inclusion criteria and were selected for final analysis. Results: In 12 studies ( n = 350), decrease in heart rate (HR) and in 4 studies ( n = 128), decrease in blood pressure (BP) was significant. In 15 studies ( n = 320), left ventricular mass index (LVMi) changes were significant. In 9 studies ( n = 202), the early diastole to peak velocity flow in late diastole (E/A ratio) was evaluated, and in 5 of them ( n = 141), the improvement was significant. Eighteen studies ( n = 366) examined changes in left ventricular ejection fraction (LVEF), 5 of which ( n = 171) reported that these changes were significant. Decrease of left ventricular end-diastolic diameter was reported in only 2 studies ( n = 27). Conclusion: We found that first-generation SSAs have a beneficial effect on cardiac parameters such as HR and LVMi. For other parameters such as LVEF, BP, LV diameter, and E/A ratio, we were not able to draw a firm conclusion.

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Introduction:During the library loan process, the printed resources can be a carrier of pathogenic bacteria. In this study, it was tried to compare the Bacterial Contamination Rates and their antibiotic sensitivity pattern in printed resources of a hospital and a non-hospital library.Methods:This is a cross-sectional study. Returning books from the Al-Zahra hospital library and library of Sciences faculty of Isfahan University provides the research community. The sample size, 96 cases, was calculated using quota sampling. For sampling sterile swab dipped in trypticase soy broth medium and transfer trypticase soy broth medium were used. To identify different type of isolated bacteria from Gram-staining test and biochemical tests such as; TSI, IMViC and etc., were used.Results:76 (79.2%) and 20 (20.8%) of cultured samples were negative and positive, the respectively. Of 20 positive samples, 11 samples (55%) belong to the family Enterobacteriaceae that after detecting by Differential teste identified all 11 samples of Enterobacter that all of them were sensitive to Gentamicin and Ofloxacin. Also the most resistance to Nitrofurantoin and Amikacin was observed. 9 cases remained (45%) were coagulase-negative Staphylococcus that all of them were sensitive to the Trimethoprim-sulfamethoxazole and Cephalexin antibiotics also the most resistance to Cefixime was observed.Conclusion:Considering that the Enterobacter sp and coagulase-negative Staphylococcus were separated from the books, the books as well as other hospital and medical equipment can transmit the infection to librarians, library users, patients and hospital staff, and also it can produce serious infections in patients with immune deficiency.

BackgroundKnowledge economy has become increasingly broad over the years and identification of core journals in this field can be useful for librarians in journal selection process and also for researchers to select their studies and finding Appropriate Journal for publishing their articles. Present research attempts to determine core journals of Knowledge Economy indexed in LISTA (Library and Information Science and Technology).MethodsThe research method was bibliometric and research population include the journals indexed in LISTA (From the start until the beginning of 2011) with at least one article a bout “knowledge economy”. For data collection, keywords about “knowledge economy”–were extracted from the literature in this area–have searched in LISTA by using title, keyword and abstract fields and also taking advantage of LISTA thesaurus. By using this search strategy, 1608 articles from 390 journals were retrieved. The retrieved records import in to the excel sheet and after that the journals were grouped and the Bradford’s coefficient was measured for each group. Finally the average of the Bradford’s coefficients were calculated and core journals with subject area of “Knowledge economy” were determined by using Bradford’s formula.FindingsBy using Bradford’s scattering law, 15 journals with the highest publication rates were identified as “Knowledge economy” core journals indexed in LISTA. In this list “Library and Information update” with 64 articles was at the top. “ASLIB Proceedings” and “Serials” with 51 and 40 articles are next in rank. Also 41 journals were identified as beyond core that “Library Hi Tech” with 20 articles was at the top.ConclusionIncreased importance of knowledge economy has led to growth of production of articles in this subject area. So the evaluation of journals for ranking these journals becomes a very challenging task for librarians and generating core journal list can provide a useful tool for journal selection and also quick and easy access to information. Core journal list and beyond core journal list obtained from this study can be used by librarians and researchers in this field.

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