Angka kejadian kutil kelamin (KK) di seluruh dunia terus meningkat. Sampai saat ini belum terdapat terapi yang lebih unggul dibanding dengan terapi lainnya. Krim 5-fluorourasil (5-FU) 5% merupakan salah satu terapi untuk KK pada meatus uretra dan uretra. Krim 5-FU 5% adalah antimetabolit pirimidin fluorinated yang memiliki fungsi sebagai agen antineoplastik dengan menghambat sintesis DNA. Seorang pasien laki-laki berusia 27 tahun dengan KK tipe kondiloma akuminta (KA) di meatus uretra dan uretra. Pada meatus uretra dan uretra tampak lesi papula ukuran 0,3x0,5x0,2 cm, sewarna kulit dan mukosa dengan permukaan yang tidak rata, pemeriksaan acetowhite positif, dan pemeriksaan polymerase chain reaction (PCR) positif untuk HPV tipe 6. Pasien diterapi dengan krim 5-FU 5% yang diaplikasikan 3 hari berturut-turut setiap minggu per siklus. Setelah mengaplikasikan krim 5-FU 5% selama 3 siklus, didapatkan lesi pada meatus uretra dan uretra menghilang pada pengamatan hari ke-29 serta tidak timbul lesi baru hingga hari ke-180. Hasil, krim 5-FU 5% untuk KK pada meatus uretra dan uretra memiliki efektivitas yang bervariasi, berkisar 25-95%, dan rekurensi sebesar 50%. Penggunaan krim 5-FU 5% efektif untuk lesi KK berukuran kecil pada meatus uretra dan uretra, dapat diaplikasikan sendiri oleh pasien, mudah digunakan, dan murah. Simpulan, krim 5-FU 5% merupakan terapi yang efektif untuk KK di meatus uretra dan uretra.
Gonore adalah infeksi menular seksual (IMS) yang disebabkan oleh Neisseria gonorrhoeae (N. gonorrhoeae). Salah satu manifestasi klinis gonore pada wanita adalah servisitis yang sebagian besar asimtomatik dan bila tidak diterapi servisitis gonore pada wanita hamil dapat menimbulkan komplikasi pada ibu, kehamilan, dan janin. Tujuan penelitian ini mengetahui prevalensi servisitis gonore pada wanita hamil di Rumah Sakit Khusus Ibu dan Anak (RSKIA) Kota Bandung tahun 2015. Penelitian ini merupakan penelitian deskriptif dengan desain potong lintang. Subjek penelitian adalah 100 wanita hamil dengan bahan pemeriksaan adalah apus endoserviks. Diagnosis servisitis gonore ditegakkan jika pada sedian apus gram ditemukan jumlah polimorfonuklear (PMN) >30/lapang pandang besar (lpb) dan diplokokus gram negatif intraseluler, serta hasil PCR N. gonorrhoeae positif. Hasil PCR N. gonorrhoeae pada seluruh subjek penelitian negatif. Namun, 41 orang (41%) subjek penelitian ditemukan jumlah PMN >30/lpb, tanpa diplokokus gram negatif intraseluler, dan didiagnosis servisitis nongonore. Simpulan penelitian ini, yaitu prevalensi servisitis gonore pada wanita hamil di RSKIA Kota Bandung tahun 2015 adalah 0%. Hasil tersebut diduga karena karakteristik sebagian besar subjek penelitian tidak termasuk ke dalam risiko tinggi mengidap IMS.
Background Molluscum contagiosum (MC) is a benign disease of the skin and mucous membrane caused by a poxvirus. To date, there is no standard therapy used for the treatment of MC. Using 10% of potassium hydroxide (KOH) once or twice a day and 20% KOH once a day are often applicable to MC lesions both in children and adults. Nevertheless, the usage of 20% KOH twice a day still has not been reported. Purpose This case series aimed to show the efficacy and side effects of once- or twice-daily application of 20% KOH solution for MC lesions due to sexually transmitted infections (STIs) in adults. Patients and Methods Three cases of MC on the genital were applied once or twice daily and one case of MC on the face was applied twice daily using 20% KOH solution. Results As a result, the application of 20% KOH twice daily showed the improvement of MC lesions on the face on day 7 and MC lesions on the genital on day 20. Meanwhile, once-daily application of 20% KOH showed diminished MC lesions on genital on day 25–31 after treatment. There were tolerable side effects that occurred in this treatment, such as stinging and burning sensation several minutes after application, erosions, and post-inflammatory hypo- and hyper-pigmentation. Conclusion The 20% KOH solution twice daily on MC lesions in adults is effective, practical, and inexpensive.
Background: Sexually transmitted infections (STIs) are major health problem. Until today, the prevalence of STIs is still high and the incidence is increasing. Almost half of STIs new cases occur in adolescents and young adults. It is assumed that there is a positive correlation of knowledge about STIs with attitude and practices; therefore, giving proper information of STIs to adolescents could influence their safe sexual practices, and further, it can prevent STIs to occur. The objective of this study is to discover knowledge and attitude of senior high school students in Jatinangor towards STIs. Methods: This descriptive study was conducted in Sekolah Menengah Atas Persatuan Guru Republik Indonesia (SMA PGRI) Jatinangor and Sekolah Menengah Atas Negeri (SMAN) Jatinangor from May to September 2013. Questionnaires were completed by 278 respondents selected by stratified cluster random sampling. Results: More than half respondents had poor knowledge about STIs (56.5%) while 53.2% of the respondents had positive attitude towards STIs. Most mentioned choices as the information source of STIs were teacher (66.5%), followed by television/radio (45.3%), friends (37.8%), newspaper/magazine (21.2%), mother (16.2%), sibling (7.2%), and father (6.5%). Conclusions:More detail information about STIs is needed by adolescents as a way to encourage safe sexual practices. Teacher and parents are expected to be the source information of STIs while mass media can also be used to educate adolescents. Education on STIs for teachers is also needed since they are as the main source for educating the adolescents. [AMJ.2015;2(4):
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