Background:The management of orofacial pain in Indonesia has not been well performed, which consequently led to an increase in the orofacial pain occurrences and a decreased quality of life. One of the possible reasons for this particular matter is the lack of evaluation on the risk factors that might induce orofacial pain in some individuals.Objective:The objective of the current study was to evaluate the risk factors of orofacial pain on productive age population in West Java province, Indonesia.Methods:One thousand and fifty-six participants (522 males; 534 females) were recruited for the study. A questionnaire that consists of demographic questions and questions evaluating several assumed risk factors for orofacial pain was used in a single interview. All data was analyzed by using Chi Square test to test the significance, Odds Ratio (OR), as well as Relative Risk (RR) by using SPSS version 23 (IBM Statistic, USA).Results:The result of the current study revealed that bruxism (p<0.01), daytime clenching (p<0.01), and unilateral chewing (p<0.01) were significantly related to the occurrence of orofacial pain. It was also found that participants who performed multitude of heavy liftings at work have an increased risk (RR=1.19: 95% CI: 1.04 – 1.35) of having orofacial pain compared to those who do not.Conclusion:Risk factors for the occurrence of orofacial pain on productive age population in Indonesian sample consisted of oral parafunctional habits and non-parafunctional habits, such as heavy lifting. Further study in this particular topic is of importance.

Background Dental caries is a widespread disease that causes dental tissue destruction and leads to local and general complications. Gram-positive bacteria including Streptococcus mutans , Streptococcus sanguinis , and Enterococcus faecalis take part in dental caries formation. Gram-positive bacteria have cell walls that consistof a thick layer of peptidoglycan which maintains the strength and rigidity of the bacteria, as well as bacteria guard from internal osmotic pressure. The biosynthesis of peptidoglycan involves many enzymes, including the Mur family, penicillin binding protein (PBP), and sortases. Purpose This research has the intention to screen and examine the antibacterial compound of edible plant Kemangi ( Ocimum basilicum L.) in terms of how it fights against some oral pathogenic bacteria of E. faecalis ATCC 29212, S. mutans ATCC 25175, and S. sanguinis ATCC 10566. Materials and Methods The O. basilicum L. was macerated by several organic solvents to obtain the extracts, before then being purified using several combinations of chromatography methods and the compound was discovered via spectroscopic methods. For the assay against bacteria, the extracts and compounds were tested using agar well diffusion and microdilution assay. Results The isolated compound was identified as β-sitosterol. The compound activity against bacteria was evaluated by in vitro assay against S. sanguinis ATCC 10566 and E. faecalis ATCC 29212 with the MIC and MBC value of 25,000 and 50,000 ppm, respectively. The compound was also tested by in silico study using the molecular docking method. The molecular interaction between β-sitosterol and the protein target showed a lower binding affinity value than the native ligand and other positive controls for each protein. Based on the amino acid residue bound to the ligands, β-sitosterol on MurA and SrtA is not competitive to the positive control, showing potential as a natural antibacterial agent. Meanwhile, on the MurB and PBP, β-sitosterol and positive control do compete with each other. Conclusion The compound, isolated from O. basilicum L. leaf, was determined as β-sitosterol, which has the molecular formula C 29 H 50 O. The antibacterial activity of β-sitosterol by in vitro assay showed weak antibacterial activity, yet exhibited the potential to inhibit the biosynthesis of peptidoglycan and prevent bacteria cell wall formation by inhibiting MurA and SrtA activity via docking simulation.

ABSTRAKPada lansia terjadi suatu proses menghilangnya secara perlahan kemampuan jaringan untuk memperbaiki diri yang disebut proses menua. Proses tersebut berpengaruh terhadap gigi dan jaringan periodontal sehingga mengakibatkan kehilangan gigi. Jika kehilangan gigi tidak diberi perawatan dapat mengganggu fungsi dan aktivitas rongga mulut sehingga akan mempunyai dampak pada kualitas hidupnya. Penelitian ini bertujuan untuk mengetahui gambaran kualitas hidup pasien lansia pengguna gigi tiruan lepasan di Instalasi Prostodonsia RSGM Unpad. Jenis penelitian adalah deksriptif dengan teknik pengambilan sampel menggunakan teknik populasi terjangkau dengan minimal sampling. Data dikumpulkan dari 31 pasien lansia pengguna gigi tiruan lepasan di Instalasi Prostodonsia RSGM Unpad. Kualitas hidup diukur dengan menggunakan kuesioner GOHAI. Hasil penelitian menunjukkan bahwa dimensi fungsi fisik berada pada kriteria cukup, dimensi nyeri dan ketidaknyamanan berada pada kriteria baik dan dimensi aspek psikososial berada pada kriteria baik. Kesimpulan penelitian menunjukkan kualitas hidup pasien lansia pengguna gigi tiruan lepasan di Instalasi Prostodonsia RSGM Unpad dikategorikan baik. Kata kunci: gigi tiruan lepasan; kualitas hidup; lansiaABSTRACT: Description of quality of life on elderly patients with removable denture at RSGM Unpad. The elderlies are prone to the process of the gradual decreasing ability of the tissue for self-healing. This process greatly affects the dental structure and periodontal tissue leading to tooth decay. When it is not properly treated, it may disturb oral functions and activities influencing their life quality. This research, therefore, aims to obtain the description of quality of life on elderly patients with removable denture at the Prosthodontic Clinic RSGM Unpad. Research was conducted with a descriptive method using the consecutive technique sampling method. Data were collected from 31 elderly patients with removable denture at the Prosthodontic Clinic RSGM Unpad and quality of life was measured by GOHAI questionnaire. The results showed that the dimensions of physical function fell into the adequate criteria, while the dimensions of pain and inconvenience and psychosocial aspects were considered good. It can be concluded that the general quality of life on elderly patients with removable denture at the Prosthodontic Clinic RSGM Unpad were good.

Introduction: Temporomandibular joint disorders is a pathologic conditions as a caused of musculoskeletal pain and dysfunction syndrome in stomatognathic system. This disorder was suffered in the population and affected the quality of life. This study was done to know how was the condition of temporomandibular joint disorders in the student of Faculty of Dentistry Universitas Padjadjaran population. Another objective of this study was the diagnosis classification of revised RDC-TMD Axis I could be applicated in Indonesian population, and to calibrate the diagnostic. Methods: The research sample was 65, with 43 female and 22 male. Result: The result showed that 50% of the student of Faculty of Dentistry Universitas Padjadjaran minimally suffered one diagnosis of temporomandibular joint disorders; with the most disorder was disc displacement with reduction, in left or right joint, followed by myofacial pain with limited opening. Conclusion: The conclusion of this research there was a high percentage of temporomandibular joint disorders in student population based on Revised Research Diagnosis Criteria for Temporomandibular Joint Disorders 2010, with the most disorder were disc displacement with reduction. So, it was important to socialize this sign and symptom of these disorders to community.

Objective(s) As the most complained oral problems in Indonesia, the therapy of orofacial pain has to be constantly evaluated. The objective of the current study was to evaluate the effectiveness of orofacial pain therapy in Indonesia. Method(s) This study recruited 5412 (3816 female; 1596 male) participants from 27 districts in West Java province. Half of the participants (2714) were recruited from those who were treated at community health centers whilst the rest were those who were treated at private dental clinics. A Likert-scale questionnaire that consists of nine questions that were divided to three subsections was used. The first subsection of the questionnaire evaluated the participants' post-therapy basic oral functions (three questions), and the second part evaluated the participants' post-therapy pain intensity and frequency (three questions), whilst the last part evaluated the participants' post-therapy activities (three questions). All data were then cross-tabulated and correlated by using Spearman correlation. Result The current study revealed that out of 5412 participants, 4023 (74.33%) participants claimed that the therapy has enabled them to perform their work activity as usual, whilst 2576 (59.2%) claimed that the therapy has decreased the intensity of the pain moderately. A significant (p < 0.01) correlation (r = 0.1) between the type of dental facility visited and the total score of the therapy effectiveness was revealed. Conclusion The therapy of orofacial pain in Indonesian sample was proven to be effective. Further study evaluating the reasons underlying the current results is of importance.