No abstract
Background: Lungs are the major organs involved by a number of infectious, inflammatory and occupational hazards. They are also involved secondarily by all forms of terminal events like cardiovascular events. Autopsy is a part of pathology that serves as an important tool to identify the cause and manner of death and to learn about methods to prevent them. Methods: This is a retrospective study conducted on the autopsy specimens received in the department of pathology from 1 January 2020 to 31 December 2021. Gross findings were noted at the time of autopsy and the specimen was subjected to routine histopathological processing and hematoxylin and eosin staining. Histopathological findings were noted. Results: Out of total 78 cases, 30.17% shows Congestion and oedema, 24.65% shows Pneumonia. 10.95% and 8.21% shows interstitial changes in the form of interstitial pneumonia or mononuclear interstitial infiltrate and Diffuse alveolar damage respectively, 6.84% shows emphysematous changes and 5.84% shows chronic passive venous congestion. 4.1% cases shows findings of tuberculosis and only 1 case was of lung abscess, metastatic papillary renal cell carcinoma and fibrin thrombi each. Highest number of cases (32) belonged to 16-30 age group. Least number of cases (2) were from >75 age group.
<p class="abstract"><strong>Background:</strong> Dengue is an endemic in tropical and sub-tropical regions of the world and also in various parts of India. Recent evidence indicates that platelet indices can be used to assess the severity and prognosis of dengue. This study aimed to assess the role of the platelet indices-mean platelet volume (MPV), platelet distribution width (PDW), platelet to large cell ratio (P-LCR), plateletcrit (Pct) and hematological parameters like hemoglobin (Hb), hematocrit (Hct) with the platelet count in dengue NS1 antigen positive cases.</p><p class="abstract"><strong>Methods:</strong> An observational cross-sectional study conducted on cases of dengue over a period of 3 months admitted with serological positivity (NS1 antigen) in a tertiary care hospital, Loni. The platelet indices like MPV, PDW, Pct, P-LCR and hematological parameters like Hb, Hct were noted using Sysmex XN-3100 Automated hematology analyzer and compared with platelet count.</p><p class="abstract"><strong>Results:</strong> Relationship between various platelet indices like MPV, PDW, P-LCR and PCT and hematological parameters like Hb, TLC and Hct were related with platelet count. Dengue positive cases were inversely related to MPV, PDW, P-LCR, Hb and Hct and directly related to Pct. In the present study Pct, P-LCR, Hb and Hct were statistically significant in correlation with platelet count.</p><p class="abstract"><strong>Conclusions:</strong> Pct, P-LCR, Hb and Hct along with platelet count can be used to assess the predictive outcomes in case of dengue infection.</p><p>.</p>
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