ABSACFMeasurements of thermoelastic and ablative stress transients generated by pulsed lasers in tissue samples have been made using fast time-response (nanosecond) piezoelectric film transducers. Studies of the ablation of cornea using excimer and CO2 lasers, and of vascular tissue using excimer, dye and solid-state lasers are described. It is shown that useful information on the pulsed laser interaction can be gained from these measurements.
Pulsed laser studies of the attenuation properties and ablation characteristics of vascular tissue in a liquid environment are reported. Acoustic waves produced by the thermoelastic effect and high fluence ablation have been studied, together with ablative removal rates for diseased and healthy tissue samples using the KrF, XeCl, and frequency-doubled YAG lasers. Tissue attenuation coefficients, ablation thresholds, and time scales are reported and compared with those for samples in air.
Nanosecond-time-resolved photoacoustic transducers have been used to study the subthreshold and ablation response of vascular tissue irradiated with short laser pulses at 248, 308, and 532 nm. Attenuation coefficients, ablation thresholds, and ablation time scales can be obtained in this way providing new information on the laser-tissue interaction problem.
The ablative removal of vascular tissue and accompanying acoustic transients have been studied in a liquid environment using KrF and XeCl excimer lasers and a frequency doubled YAG laser.
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