Objective: the objective of this study is to compare the clinical effectiveness of a relatively new locally manufactured articaine (Artpharmadent 4% 1/100.000, made in Egypt) versus imported articaine (Artinibsa 4% 1:100.000, made in France) in buccal infiltration anesthesia during extraction of primary molars. Subjects and Methods: A prospective, randomized, split-mouth comparative study was conducted on children aged from 6 -10 years old having bilateral badly decayed mandibular or maxillary primary molars. Children were randomly chosen from the outpatient clinic of paediatric dentistry department, Cairo University. Split-mouth technique was followed to give buccal infiltrations of Artpharmadent on one side and Artinibsa on the other at separate visits. Child pain and behaviour were assessed using Wong-Baker FACES pain rating scale and face, leg, activity, cry and consolability (FLACC) Behavioural Pain Assessment Scale. Results: Both anaesthetic types showed comparable and high clinical effectiveness in pain control during extraction. FLACC behavioural pain scale showed insignificant difference with both local anaesthetics. Conclusion: locally manufactured articaine buccal infiltration anesthesia is effective as imported one. It showed deep and painless alternative to anaesthetize primary molars and related supporting tissues.
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